Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features
Combined Automated Annotation using Multiple IEA Methods
Pa0148 from Pseudomonas aeruginosa catalyzes the deamination of adenine.
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Purified PA0148 deaminates adenine to hypoxanthine with kcat/Km above 10^5 M-1 s-1 and does not act on adenosine.
"All of these proteins will deaminate adenine to produce hypoxanthine with k(cat)/K(m) values that exceed 10(5) M(-1) s(-1)."
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PA0148 is a mononuclear zinc amidohydrolase.
"Metal binding residues for Pa0148 include an HxH motif from the C-terminus of β-strand 1 (His-16 and His-18), a histidine from the C-terminus of β-strand 5 (His-196) and an aspartate from the C-terminus of β-strand 8 (Asp-277)."