ACTRT3: which of actin's residues survive, and has PAINT already rejected this term next door?

Generated by uv run python analyze_actrt3.py. Every number is computed at run time from
the UniProt REST API, RCSB coordinate files, QuickGO, and the repository's PANTHER/PAINT
export. Nothing here is hardcoded; re-running regenerates this file.

Structural machinery (contact detection, alignment, substitution classing, two-scheme
sensitivity) is deliberately identical to genes/human/ACTL8/ACTL8-bioinformatics/analyze_actl8.py
so the tallies are directly comparable with that merged sibling review.

Headline

Nucleotide site, 19 contacts (PDB 2BTF chain A): ACTRT3 = 15 identical, 2 conservative, 2 non-conservative, 0 gaps.
Profilin surface, 21 contacts (same structure, profilin chain P): ACTRT3 = 14 identical, 2 conservative, 5 non-conservative, 0 gaps.
Filament protomer interface, 38 contacts (PDB 6DJO, chain C): ACTRT3 = 13 identical, 5 conservative, 19 non-conservative, 1 gaps.

Controls on the same three measurements:

Protein	Role in the comparison	Nucleotide site	Profilin surface	Filament interface
ACTRT3	target	15 identical, 2 conservative, 2 non-conservative, 0 gaps	14 identical, 2 conservative, 5 non-conservative, 0 gaps	13 identical, 5 conservative, 19 non-conservative, 1 gaps
ACTB	human beta-actin; polymerises; IBA donor	19 identical, 0 conservative, 0 non-conservative, 0 gaps	21 identical, 0 conservative, 0 non-conservative, 0 gaps	37 identical, 1 conservative, 0 non-conservative, 0 gaps
ACTG1	human gamma-actin; polymerises; IBA donor	19 identical, 0 conservative, 0 non-conservative, 0 gaps	21 identical, 0 conservative, 0 non-conservative, 0 gaps	37 identical, 1 conservative, 0 non-conservative, 0 gaps
ACTA1	human alpha-skeletal actin; polymerises; IBA donor	18 identical, 1 conservative, 0 non-conservative, 0 gaps	20 identical, 1 conservative, 0 non-conservative, 0 gaps	38 identical, 0 conservative, 0 non-conservative, 0 gaps
ACTC1	human alpha-cardiac actin; polymerises; IBA donor	18 identical, 1 conservative, 0 non-conservative, 0 gaps	20 identical, 1 conservative, 0 non-conservative, 0 gaps	38 identical, 0 conservative, 0 non-conservative, 0 gaps
Arp53D	Drosophila actin-like 53D; DIVERGENT and polymerises; IBA donor	16 identical, 3 conservative, 0 non-conservative, 0 gaps	18 identical, 2 conservative, 1 non-conservative, 0 gaps	29 identical, 4 conservative, 5 non-conservative, 0 gaps
ACTR1A	human alpha-centractin/Arp1; polymerises in dynactin	14 identical, 4 conservative, 1 non-conservative, 0 gaps	16 identical, 4 conservative, 1 non-conservative, 0 gaps	20 identical, 8 conservative, 10 non-conservative, 0 gaps
ACTR1B	human beta-centractin/Arp1B; polymerises in dynactin	14 identical, 4 conservative, 1 non-conservative, 0 gaps	16 identical, 3 conservative, 2 non-conservative, 0 gaps	21 identical, 7 conservative, 10 non-conservative, 0 gaps
ACTR10	human Arp11; does NOT homopolymerise	9 identical, 2 conservative, 8 non-conservative, 0 gaps	6 identical, 2 conservative, 13 non-conservative, 0 gaps	9 identical, 5 conservative, 12 non-conservative, 12 gaps
ACTR2	human Arp2	16 identical, 3 conservative, 0 non-conservative, 0 gaps	10 identical, 4 conservative, 7 non-conservative, 0 gaps	15 identical, 7 conservative, 16 non-conservative, 0 gaps
ACTR3	human Arp3	14 identical, 4 conservative, 1 non-conservative, 0 gaps	9 identical, 3 conservative, 9 non-conservative, 0 gaps	5 identical, 3 conservative, 29 non-conservative, 1 gaps
ACTL8	human actin-like 8; merged review REMOVEd its filament rows	11 identical, 3 conservative, 5 non-conservative, 0 gaps	6 identical, 4 conservative, 11 non-conservative, 0 gaps	8 identical, 3 conservative, 24 non-conservative, 3 gaps
ACTRT1	human ARP-T1; same CDD clade as ACTRT3	14 identical, 2 conservative, 3 non-conservative, 0 gaps	13 identical, 4 conservative, 4 non-conservative, 0 gaps	13 identical, 8 conservative, 17 non-conservative, 0 gaps
ACTRT2	human ARP-T2 / ARPM2; same CDD clade as ACTRT3	13 identical, 4 conservative, 2 non-conservative, 0 gaps	13 identical, 4 conservative, 4 non-conservative, 0 gaps	14 identical, 6 conservative, 18 non-conservative, 0 gaps
ACTL7A	human actin-like 7A; PT protein, ACTRT3 co-IP partner	12 identical, 2 conservative, 5 non-conservative, 0 gaps	11 identical, 5 conservative, 5 non-conservative, 0 gaps	13 identical, 1 conservative, 24 non-conservative, 0 gaps
ACTL7B	human actin-like 7B	13 identical, 0 conservative, 6 non-conservative, 0 gaps	7 identical, 3 conservative, 10 non-conservative, 1 gaps	14 identical, 2 conservative, 22 non-conservative, 0 gaps
ACTL9	human actin-like 9	11 identical, 4 conservative, 4 non-conservative, 0 gaps	8 identical, 4 conservative, 9 non-conservative, 0 gaps	11 identical, 5 conservative, 22 non-conservative, 0 gaps
ACTL10	human actin-like 10	7 identical, 3 conservative, 4 non-conservative, 5 gaps	4 identical, 0 conservative, 15 non-conservative, 2 gaps	3 identical, 2 conservative, 13 non-conservative, 20 gaps

Ranking within the divergent clade

Chemically compatible contacts (identical + conservative) for the eight divergent human
actin-like / actin-related-T proteins, all computed in this run:

Contact set	n	Ranking, best first
nucleotide_site	19	ACTRT3 17, ACTRT2 17, ACTRT1 16, ACTL9 15, ACTL7A 14, ACTL8 14, ACTL7B 13, ACTL10 10
profilin_interface	21	ACTRT1 17, ACTRT2 17, ACTRT3 16, ACTL7A 16, ACTL9 12, ACTL7B 10, ACTL8 10, ACTL10 4
filament_interface	38	ACTRT1 21, ACTRT2 20, ACTRT3 18, ACTL7B 16, ACTL9 16, ACTL7A 14, ACTL8 11, ACTL10 5

Alignment sensitivity

Same tallies under a second substitution matrix and gap model, for ACTRT3 only:

Scheme	Nucleotide site	Profilin surface	Filament interface
BLOSUM62/-11/-1	15/2/2/0	14/2/5/0	13/5/19/1
BLOSUM45/-14/-2	15/2/2/0	14/2/5/0	13/5/19/1

(identical / conservative / non-conservative / gap)

Per-residue tables

Nucleotide site (2BTF chain A, ['ATP', 'SR'], 4.0 Å)

Structure residue	Contacts	min dist (Å)	ACTRT3	ACTB	Arp53D	ACTR1A	ACTR10	ACTL8	ACTRT1	ACTRT2
G13 (GLY)	ATP	3.32	G13	G13	G19	G17	G21	G11	G17	G17
S14 (SER)	ATP	2.87	S14	S14	S20	S18	E22 **	S12	S18	S18
G15 (GLY)	ATP	2.64	G15	G15	G21	G19	A23 ~	G13	G19	G19
M16 (MET)	ATP	2.66	M16	M16	V22 ~	V20 ~	F24 ~	F14 ~	L20 ~	F20 ~
K18 (LYS)	ATP	3.37	K18	K18	K24	K22	K26	K16	K22	K22
Q137 (GLN)	SR	3.02	Q136	Q137	Q142	Q142	S123 **	Q132	H140 **	Q141
G156 (GLY)	ATP	3.24	G155	G156	G161	G161	G142	G151	G159	G160
D157 (ASP)	ATP	2.64	A156 **	D157	D162	D162	Y143 **	Y152 **	D160	D161
G158 (GLY)	ATP	2.88	G157	G158	G163	G163	R144 **	G153	G161	A162 ~
V159 (VAL)	ATP	3.13	V158	V159	V164	V164	E145 **	L154 ~	V162	V163
G182 (GLY)	ATP	3.43	G181	G182	G187	G187	G168	G177	G185	G186
K213 (LYS)	ATP	2.87	K212	K213	K218	K218	K211	Q208 **	K216	K217
E214 (GLU)	ATP	2.8	E213	E214	E219	E219	A212 **	M209 **	E217	K218 **
G301 (GLY)	ATP	3.45	G298	G301	G302	G302	G307	G299	G302	G303
G302 (GLY)	ATP	2.94	G299	G302	G303	G303	G308	G300	G303	G304
T303 (THR)	ATP	3.35	S300 ~	T303	T304	S304 ~	T309	N301 **	T304	T305
M305 (MET)	ATP	3.55	S302 **	M305	M306	L306 ~	M311	L303 ~	L306 ~	L307 ~
Y306 (TYR)	ATP	3.23	F303 ~	Y306	F307 ~	F307 ~	L312 **	Y304	L307 **	F308 ~
K336 (LYS)	ATP	3.08	K333	K336	R337 ~	L337 **	A350 **	N334 **	C337 **	W338 **

Profilin surface (same structure, contacts to the profilin chain)

Structure residue	Contacts	min dist (Å)	ACTRT3	ACTB	Arp53D	ACTR1A	ACTR10	ACTL8	ACTRT1	ACTRT2
K113 (LYS)	GLU	3.07	L112 **	K113	K118	R118 ~	S99 **	P108 **	R116 ~	R117 ~
Y133 (TYR)	HIS	3.39	Y132	Y133	Y138	F138 ~	L119 **	L128 **	Y136	Y137
Y166 (TYR)	ARG, LYS, SER, THR	2.99	F165 ~	Y166	Y171	Y171	Y152	H161 **	F169 ~	F170 ~
E167 (GLU)	ARG, THR	3.5	E166	E167	E172	E172	E153	Q162 **	E170	E171
Y169 (TYR)	ARG, ASN, GLY, HIS, ILE	2.97	Y168	Y169	F174 ~	F174 ~	I155 **	R164 **	Y172	Y173
A170 (ALA)	ILE	3.85	C169 **	A170	A175	A175	P156 **	P165 **	S173 **	S174 **
P172 (PRO)	ILE	3.5	P171	P172	P177	P177	L158 **	P167	P175	P176
H173 (HIS)	PHE	3.41	H172	H173	H178	H178	N159 **	A168 **	H176	H177
K284 (LYS)	PHE, VAL	3.8	K281	K284	N285 **	K285	Q290 **	S282 **	K285	K286
C285 (CYS)	PHE, VAL	3.29	C282	C285	C286	S286 **	C291	C283	C286	C287
D286 (ASP)	LYS, PHE, SER, VAL	2.86	D283	D286	D287	D287	P292 **	E284 ~	D287	D288
V287 (VAL)	VAL	2.82	T284 **	V287	M288 ~	M288 ~	I293 ~	I285 ~	T288 **	T289 **
D288 (ASP)	LYS	3.29	G285 **	D288	D289	D289	D294	S286 **	D289	D290
R290 (ARG)	VAL	3.08	R287	R290	R291	R291	R296	R288	Q291 **	Q292 **
M355 (MET)	HIS	3.89	M352	M355	M356	M356	R371 **	E353 **	M356	M357
E361 (GLU)	LYS	3.22	E358	E361	E362	E362	Y377 **	E359	D362 ~	D363 ~
E364 (GLU)	GLU, LYS	3.12	E361	E364	E365	E365	Q380 **	E362	E365	E366
H371 (HIS)	ARG	2.82	H368	H371	H372	H372	K410 ~	H363	Q372 **	Q373 **
R372 (ARG)	ASN, GLU, GLY, THR, TYR	2.59	Q369 **	R372	R373	R373	R411	M364 **	R373	R374
K373 (LYS)	GLY, HIS	3.37	R370 ~	K373	K374	K374	A412 **	R365 ~	R374 ~	R375 ~
F375 (PHE)	ARG, ASP, GLY	3.31	F372	F375	F376	F376	S414 **	M366 ~	F376	F377

Filament protomer interface (6DJO)

Structure residue	Contacts	min dist (Å)	ACTRT3	ACTB	Arp53D	ACTR1A	ACTR10	ACTL8	ACTRT1	ACTRT2
P38 (PRO)	A	3.61	A38 **	P38	P44	P42	gap	P37	C42 **	L42 **
R39 (ARG)	A, B	3.43	K39 ~	R39	R45	K43 ~	gap	C38 **	K43 ~	K43 ~
H40 (HIS)	A	3.39	G40 **	H40	H46	H44	gap	K39 ~	F44 **	F44 **
Q41 (GLN)	A	3.86	Q41	Q41	L47 **	V45 **	gap	E40 **	N45 ~	Q45
G42 (GLY)	A	3.35	S42 **	G42	N48 **	R46 **	gap	N41 **	V46 **	A46 ~
V43 (VAL)	A	3.17	gap	V43	V49	V47	gap	P42 **	P47 **	P47 **
M44 (MET)	A	3.13	R43 **	M44	L50 ~	M48	gap	G43 **	L48 ~	S48 **
V45 (VAL)	A	3.56	A44 **	V45	L51 ~	A49 **	gap	P44 **	A49 **	A49 **
M47 (MET)	A	3.79	Q46 **	M47	S53 **	A51 **	gap	Y46 **	L51 ~	A51 **
Q49 (GLN)	A	3.94	G48 **	Q49	I55 **	E53 **	gap	R48 **	Q53	Q53
K61 (LYS)	A	2.79	W60 **	K61	K67	H65 ~	P49 **	P60 **	K64	K65
R62 (ARG)	A	2.99	R61	R62	R68	R66	K50 ~	D61 **	Y65 **	Q66 **
G63 (GLY)	A	2.88	S62 **	G63	G69	G67	P51 **	gap	E66 **	E67 **
I64 (ILE)	A	3.57	S63 **	I64	I70	L68 ~	V52 ~	gap	A67 **	A68 **
L65 (LEU)	B	3.46	L64	L65	L71	L69	R53 **	gap	L68	L69
T66 (THR)	B	3.22	F65 **	T66	T72	S70 ~	V54 **	T62	H69 **	Q70 **
L67 (LEU)	B	3.85	I66 ~	L67	L73	I71 ~	V55 ~	F63 ~	L70	L71
L110 (LEU)	D	3.28	L109	L110	L115	L115	L96	L105	L113	L114
P112 (PRO)	D	3.36	P111	P112	P117	P117	P98	E107 **	P115	P116
K113 (LYS)	D	3.11	L112 **	K113	K118	R118 ~	S99 **	P108 **	R116 ~	R117 ~
H173 (HIS)	D	3.35	H172	H173	H178	H178	N159 **	A168 **	H176	H177
K191 (LYS)	B	3.91	V190 **	K191	K196	L196 **	T177 **	K186	R194 ~	Q195 **
T194 (THR)	B	3.28	K193 **	T194	L199 **	R199 **	L180 **	F189 **	F197 **	L198 **
E195 (GLU)	B	3.1	N194 **	E195	E200	K200 **	E181	K190 **	A198 **	A199 **
G197 (GLY)	B	3.64	G196	G197	G202	G202	C183 **	D192 **	G200	G201
T202 (THR)	B	3.55	S201 ~	T202	T207	S207 ~	S188 ~	C197 **	C205 **	C206 **
T203 (THR)	B	3.32	A202 **	T203	S208 ~	S208 ~	V189 **	L198 **	I206 **	Q207 **
A204 (ALA)	A	3.14	S203 **	A204	A209	S209 **	A190	F199 **	L207 **	L208 **
E205 (GLU)	A	3.02	D204 ~	E205	E210	E210	K191 **	Q200 **	N208 **	D209 ~
I208 (ILE)	A	3.35	I207	I208	I213	I213	V206 ~	T203 **	V211 ~	L212 ~
E241 (GLU)	A	2.82	Q238 **	E241	E242	Y242 **	E238	Q239 **	R242 **	K243 **
L242 (LEU)	A	3.76	L239	L242	L243	L243	R239 **	L240	L243	L244
P243 (PRO)	A	3.67	P240	P243	P244	P244	P240	P241	P244	P245
D244 (ASP)	A	3.25	D241	D244	D245	D245	D251	D242	D245	D246
G245 (GLY)	A	3.44	G242	G245	G246	G246	G252	G243	G246	G247
I267 (ILE)	B	3.48	M264 ~	L267 ~	L268 ~	I268	gap	F265 ~	L268 ~	L269 ~
G268 (GLY)	D	3.88	N265 **	G268	G269	G269	gap	E266 **	G269	G270
E270 (GLU)	D	3.15	E267	E270	E271	E271	E276	P268 **	H271 **	Q272 **

~ conservative, ** non-conservative, gap no aligned residue.

PAINT's own handling of GO:0005200 inside PTHR11937

Asserted at PTN000940351 (IBD, 20250805) from 10 seeds; human recipients: ACTA1, ACTA2, ACTC1, ACTG2, ACTL10, ACTL7A, ACTL7B, ACTL9, ACTR10, ACTRT1, ACTRT2, ACTRT3.
Rejected (negated IRD) at 8 descendant nodes:

Node	Date	Other terms curated at that node	Human genes at the node
`PTN000233752`	20250805	GO:0005737, GO:0006338, GO:0006355, GO:0030234, GO:0031011	ACTR5
`PTN000233887`	20250805	GO:0000812, GO:0006338, GO:0007000, GO:0031491	ACTR6
`PTN000234048`	20250805	GO:0003729, GO:0006302, GO:0006355, GO:0031011	ACTR8
`PTN001732543`	20250805	GO:0003682, GO:0006338, GO:0006357, GO:0016514, GO:0035267	ACTL6A, ACTL6B
`PTN008986528`	20250805	GO:0005198	ACTL7A, ACTL7B
`PTN000233596`	20260416	GO:0005885, GO:0005938, GO:0034314, GO:0051015	ACTR2
`PTN000233796`	20260416	GO:0005885, GO:0034314, GO:0044396, GO:0051015	ACTR3, ACTR3B, ACTR3C
`PTN007551901`	20260416	GO:0106006	ACTR1A, ACTR1B

Nodes where the general parent GO:0005198 structural molecule activity is asserted instead:

Node	Date	GO:0005200 also rejected here	Human genes at the node
`PTN008986528`	20250805	True	ACTL7A, ACTL7B

ACTRT3's own donating nodes are ['PTN000940351', 'PTN002631484']; GO:0005200 is rejected on that path at: no node.

Donor versus recipient composition of ACTRT3's two donating nodes

`PTN000940351`

PAINT rows curated at this node: GO:0005200 (IBD, 10 seeds, 20250805)
Terms it donates to human genes: GO:0005198, GO:0005200
12 human recipients, by local identity to beta-actin:

Gene	Accession	Length	% identity to ACTB (local)
ACTA2	P62736	377	94.1
ACTC1	P68032	377	94.1
ACTA1	P68133	377	93.6
ACTG2	P63267	376	93.6
ACTRT3	Q9BYD9	372	49.7
ACTRT1	Q8TDG2	376	48.9
ACTRT2	Q8TDY3	377	48.7
ACTL7B	Q9Y614	415	44.5
ACTL7A	Q9Y615	435	44.1
ACTL9	Q8TC94	416	41.4
ACTL10	Q5JWF8	245	33.7
ACTR10	Q9NZ32	417	25.9

`PTN002631484`

PAINT rows curated at this node: GO:0015629 (IBD, 24 seeds, 20260528)
Terms it donates to human genes: GO:0015629
18 human recipients, by local identity to beta-actin:

Gene	Accession	Length	% identity to ACTB (local)
ACTB	P60709	375	100.0
ACTG1	P63261	375	98.9
ACTA2	P62736	377	94.1
ACTC1	P68032	377	94.1
ACTA1	P68133	377	93.6
ACTG2	P63267	376	93.6
POTEE	Q6S8J3	1075	92.0
ACTBL2	Q562R1	376	91.7
POTEF	A5A3E0	1075	91.7
POTEKP	Q9BYX7	375	91.5
POTEI	P0CG38	1075	91.2
POTEJ	P0CG39	1038	90.7
ACTRT3	Q9BYD9	372	49.7
ACTRT1	Q8TDG2	376	48.9
ACTRT2	Q8TDY3	377	48.7
ACTL9	Q8TC94	416	41.4
ACTL8	Q9H568	366	33.8
ACTL10	Q5JWF8	245	33.7

Relatives census, recomputed from QuickGO

ACTL8 carries 11 IBA rows; ACTRT3 carries 2; the median across the other seven divergent relatives is 2.

Gene	IBA rows	PANTHER nodes	IBA terms
ACTL10	2	PTN000940351, PTN002631484	GO:0005200, GO:0015629
ACTL7A	3	PTN000940351, PTN001377938, PTN008986520, PTN008986528	GO:0005198, GO:0005634, GO:0005737
ACTL7B	3	PTN000940351, PTN001377938, PTN008986520, PTN008986528	GO:0005198, GO:0005634, GO:0005737
ACTL8	11	PTN002631484, PTN002631586, PTN007551913	GO:0005737, GO:0005884, GO:0007409, GO:0015629, GO:0016020, GO:0019901, GO:0030424, GO:0035267, GO:0045202, GO:0048870, GO:0098973
ACTL9	2	PTN000940351, PTN002631484	GO:0005200, GO:0015629
ACTRT1	5	PTN000748066, PTN000940351, PTN002631484	GO:0003682, GO:0005200, GO:0005634, GO:0006355, GO:0015629
ACTRT2	2	PTN000940351, PTN002631484	GO:0005200, GO:0015629
ACTRT3	2	PTN000940351, PTN002631484	GO:0005200, GO:0015629

The mouse orthologue behind the only experimental evidence

Q8BXF8 = ACTT3_MOUSE (Swiss-Prot), Actin-related protein T3, genes ['Actrt3'], 369 aa.
Global identity to human ACTRT3: 79.4%; local 78.8%. Local identity to beta-actin for comparison: 47.0%.
Terms it donates: GO:0001673, GO:0033011
GO:0001673: 1 annotations, codes [('GO:0001673', 'IDA')], own experimental = True, refs ['PMID:18692047']
GO:0033011: 1 annotations, codes [('GO:0033011', 'IDA')], own experimental = True, refs ['PMID:35793634']

Its complete annotation set, so that any row without a human counterpart is visible:

GO id	Aspect	Ev	Qualifier	Reference	WITH/FROM	Resolved experimental partner
GO:0005200	MO	IBA	enables	GO_REF:0000033	MGI:MGI:87906, PANTHER:PTN000940351, RGD:1304556, SGD:S000001171, SGD:S000001855, SGD:S000002513, UniProtKB:P60709, UniProtKB:P61158, UniProtKB:P61160, dictyBase:DDB_G0269234, dictyBase:DDB_G0289811	—
GO:0005515	MO	IPI	enables	PMID:18692047	UniProtKB:Q9DAD6	Q9DAD6 ['Pfn3'] (Swiss-Prot, Mus musculus)
GO:0005515	MO	IPI	enables	PMID:18692047	UniProtKB:Q9DAD6	Q9DAD6 ['Pfn3'] (Swiss-Prot, Mus musculus)
GO:0007010	BI	IEA	involved_in	GO_REF:0000108	GO:0005200	—
GO:0015629	CE	IBA	is_active_in	GO_REF:0000033	CGD:CAL0000191211, FB:FBgn0011743, MGI:MGI:87906, MGI:MGI:87909, PANTHER:PTN002631484, PomBase:SPBC32H8.12c, RGD:1304556, RGD:621676, RGD:628837, SGD:S000001855, UniProtKB:P08023, UniProtKB:P60709, UniProtKB:P63261, UniProtKB:P68032, UniProtKB:P68133, UniProtKB:Q6QAQ1, UniProtKB:Q8I4X0, WB:WBGene00000064, WB:WBGene00000065, WB:WBGene00000066, WB:WBGene00000067, dictyBase:DDB_G0269234, dictyBase:DDB_G0275023, dictyBase:DDB_G0289487, dictyBase:DDB_G0289811	—
GO:0001673	CE	IDA	located_in	PMID:18692047	—	—
GO:0005634	CE	IEA	located_in	GO_REF:0000044	UniProtKB-SubCell:SL-0191	—
GO:0005737	CE	IEA	located_in	GO_REF:0000044	UniProtKB-SubCell:SL-0086	—
GO:0005856	CE	IEA	located_in	GO_REF:0000044	UniProtKB-SubCell:SL-0090	—
GO:0033011	CE	IDA	located_in	PMID:35793634	—	—