GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
PMID:11152476
The neural cell recognition molecule neurofascin interacts with syntenin-1 but not with syntenin-2, both of which reveal self-associating activity.
PMID:12421765
Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.
PMID:1621094
Neurexins: synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin.
PMID:18057082
A patient with vertebral, cognitive and behavioural abnormalities and a de novo deletion of NRXN1alpha.
PMID:18923512
Neuroligins and neurexins link synaptic function to cognitive disease.
PMID:19036990
Polarized targeting of neurexins to synapses is regulated by their C-terminal sequences.
PMID:19822762
Mouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments.
PMID:34135511
GluD1 is a signal transduction device disguised as an ionotropic receptor.
PMID:19896112
CNTNAP2 and NRXN1 are mutated in autosomal-recessive Pitt-Hopkins-like mental retardation and determine the level of a common synaptic protein in Drosophila.
PMID:21424692
Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia.
PMID:36115835
Quantitative fragmentomics allow affinity mapping of interactomes.
Reactome:R-HSA-6794346
NRXNs bind NLGNs
Reactome:R-HSA-6797554
ABP1 binds SHANK proteins
Reactome:R-HSA-6797568
NRXNs bind CASK:Protein 4.1
Reactome:R-HSA-6797974
LRRTMs bind NRXNs
PMID:12827191
Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.
PMID:17035546
Important contribution of alpha-neurexins to Ca2+-triggered exocytosis of secretory granules.
PMID:11470830
A stoichiometric complex of neurexins and dystroglycan in brain.
PMID:20064387
LRRTM2 functions as a neurexin ligand in promoting excitatory synapse formation.
PMID:20064388
LRRTM2 interacts with Neurexin1 and regulates excitatory synapse formation.
PMID:16242404
A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins.
PMID:22262843
High affinity neurexin binding to cell adhesion G-protein-coupled receptor CIRL1/latrophilin-1 produces an intercellular adhesion complex.
PMID:15620359
Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins.
PMID:20537373
Trans-synaptic interaction of GluRdelta2 and Neurexin through Cbln1 mediates synapse formation in the cerebellum.
PMID:21356198
Differential interactions of cerebellin precursor protein (Cbln) subtypes and neurexin variants for synapse formation of cortical neurons.
PMID:20471353
Neurexins physically and functionally interact with GABA(A) receptors.
PMID:8786425
CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins.
PMID:10892652
Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons.
PMID:19567877
Presynaptic targeting of alpha4beta 2 nicotinic acetylcholine receptors is regulated by neurexin-1beta.
PMID:14983056
Postsynaptic N-methyl-D-aspartate receptor function requires alpha-neurexins.
PMID:10520997
The structure of the ligand-binding domain of neurexin Ibeta: regulation of LNS domain function by alternative splicing.
file:human/NRXN1/NRXN1-uniprot.txt
UniProtKB Q9ULB1 (NRXN1_HUMAN) entry
file:human/NRXN1/NRXN1-deep-research-falcon.md
Falcon deep research report on NRXN1