Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Combined Automated Annotation using Multiple IEA Methods
Interaction of NE-dlg/SAP102, a neuronal and endocrine tissue-specific membrane-associated guanylate kinase protein, with calmodulin and PSD-95/SAP90. A possible regulatory role in molecular clustering at synaptic sites.
The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses.
Selective interaction of megalin with postsynaptic density-95 (PSD-95)-like membrane-associated guanylate kinase (MAGUK) proteins.
Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux.
Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis.
Docking motif-guided mapping of the interactome of protein phosphatase-1.
DGKι regulates presynaptic release during mGluR-dependent LTD.
Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.
Polarity protein complex Scribble/Lgl/Dlg and epithelial cell barriers.
The association of GPR85 with PSD-95-neuroligin complex and autism spectrum disorder: a molecular analysis.
Proteome-wide analysis of phospho-regulated PDZ domain interactions.
A reference map of the human binary protein interactome.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Quantitative fragmentomics allow affinity mapping of interactomes.
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Below-threshold PDZ-peptide measurements do not establish absence of binding; positive measurements retain fragment and modification scope.
"pairs that fell below holdup quantification threshold should not be considered as “non-interactions”"
Multimodal cell maps as a foundation for structural and functional genomics.
Cloning and characterization of NE-dlg: a novel human homolog of the Drosophila discs large (dlg) tumor suppressor protein interacts with the APC protein.
Ca2+ influx into the post-synaptic cell
kainate receptor binds glutamate
Activation of Ca-permeable Kainate receptors
RAS GEFs promote RAS nucleotide exchange
ABP1 binds SHANK proteins
SALMs 1-3 bind to PSD-95 family members
NMDA receptor trafficking through an interaction between PDZ proteins and the exocyst complex.
Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases.
Subunit-specific regulation of N-methyl-D-aspartate (NMDA) receptor trafficking by SAP102 protein splice variants.
DLG3 PDZ fragmentomics: reproducible source measurements and sequence crosswalk