GO_REF:0000002

Gene Ontology annotation through association of InterPro records with GO terms

InterPro2GO mapping from A2M domain (IPR001599) incorrectly assigns endopeptidase inhibitor activity to arthropod TEPs which have diverged to opsonin function

"[This is a curator assessment based on comparison of domain-function mapping with TEP family biology]"

GO_REF:0000043

Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping

Keyword "Immunity" appropriately maps to immune system process

"[Standard keyword mapping is appropriate for this gene]"

GO_REF:0000120

Combined Automated Annotation using Multiple IEA Methods

Subcellular location annotations are appropriate based on secretion signals and domain architecture

"[Automated localization predictions are consistent with TEP family biology]"

file:ANOGA/TEP10/TEP10-deep-research-falcon.md

Deep research summary for TEP10 gene function

TEP10 lacks direct experimental characterization but can be functionally inferred from TEP family biology as a complement-like opsonin

"No direct functional or expression studies specifically for TEP10 (AGAP010819/Q7PSK0) were retrieved"
TEPs are complement C3-like opsonins, not protease inhibitors

"Thioester-containing proteins (TEPs) are arthropod complement-like factors...They are typically secreted into the hemolymph and act as opsonins that covalently tag microbes or parasites"
Many TEP paralogs including TEP10 remain poorly characterized

"biological functions of other AgTEP members (AgTEP2-19) remain largely unexplored"