vosA (Aspergillus nidulans) — curation notes

UniProt Q5BBX1 (VOSA_EMENI). Velvet-family regulator of spore maturation/dormancy.
Member of the conidiation_regulatory_cascade module (velvet maturation tier).

• Velvet/NF-kB-like DNA-binding regulator; VosA/VelB repress spore cell-wall
  (beta-glucan) biosynthetic genes. PMID:25960370.
• Couples sporogenesis to trehalose biogenesis; expressed during conidial and
  ascospore formation. PMID:17912349.
• Core MF asserted: GO:0003700 (DNA-binding TF) from velvet NF-kB-like domain
  PMID:24391470 — note GOA has not yet annotated this MF (proposed by review).
• protein binding / identical protein binding (IPI) kept non-core (velvet complex
  interactions; uninformative MF).

2026-10-01 re-review (GOA refresh)

• No new or vanished GOA rows.
• Protein binding IPI (PMID:24391470) changed KEEP_AS_NON_CORE -> MODIFY to GO:0046982 protein
  heterodimerization activity (VosA-VelB heterodimer crystal structure).
• Added NEW GO:0003700 DNA-binding transcription factor activity (IDA, PMID:24391470): ChIP-chip,
  motif discovery and EMSA with motif deletions show sequence-specific promoter binding, and vosA
  deletion alters target transcripts. This grounds the core MF, which previously had no row.
• Added supporting text to nucleus IDA rows (PMID:21152013, PMID:17912349).