GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms.
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara.
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods.
PMID:10852928
Cartilage oligomeric matrix protein is a calcium-binding protein, and a mutation in its type 3 repeats causes conformational changes.
PMID:11084047
Mutations in cartilage oligomeric matrix protein causing pseudoachondroplasia and multiple epiphyseal dysplasia affect binding of calcium and collagen I, II, and IX.
PMID:12225811
Matrix-matrix interaction of cartilage oligomeric matrix protein and fibronectin.
PMID:15075323
Interactions between the cartilage oligomeric matrix protein and matrilins. Implications for matrix assembly and the pathogenesis of chondrodysplasias.
PMID:16051604
Cartilage oligomeric matrix protein/thrombospondin 5 supports chondrocyte attachment through interaction with integrins.
PMID:16542502
Cartilage oligomeric matrix protein is involved in human limb development and in the pathogenesis of osteoarthritis.
PMID:16611630
ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein.
PMID:17588949
Interaction of cartilage oligomeric matrix protein/thrombospondin 5 with aggrecan.
PMID:17993464
Cartilage oligomeric matrix protein protects cells against death by elevating members of the IAP family of survival proteins.
PMID:18285447
Extracellular matrix retention of thrombospondin 1 is controlled by its conserved C-terminal region.
PMID:18485748
Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin.
PMID:20551380
Proteomics characterization of extracellular space components in the human aorta.
PMID:23533145
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
PMID:25416956
A proteome-scale map of the human interactome network.
PMID:27068509
Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
PMID:29030641
Lubricin binds cartilage proteins, cartilage oligomeric matrix protein, fibronectin and collagen II at the cartilage surface.
PMID:31515488
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
PMID:32296183
A reference map of the human binary protein interactome.
PMID:32747625
Author Correction: Mutations in COMP cause familial carpal tunnel syndrome.
PMID:7670472
Pseudoachondroplasia and multiple epiphyseal dysplasia due to mutations in the cartilage oligomeric matrix protein gene.
PMID:7713493
Characterization of human and mouse cartilage oligomeric matrix protein.
Reactome:R-HSA-2424252
COMP binds collagen, fibronectin, aggrecan and matrilins
Reactome:R-HSA-2426259
COMP binds Integrin alpha5beta1, Integrin alphaVbeta3, CD47
file:human/COMP/COMP-deep-research-falcon.md
Deep research on COMP function