Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Automatic Gene Ontology annotation based on Rhea mapping

Combined Automated Annotation using Multiple IEA Methods

Role of purine nucleoside phosphorylase in interactions between 2',3'-dideoxyinosine and allopurinol, ganciclovir, or tenofovir.

Intracellular delivery of purine nucleoside phosphorylase (PNP) fused to protein transduction domain corrects PNP deficiency in vitro.

TAT-mediated intracellular delivery of purine nucleoside phosphorylase corrects its deficiency in mice.

Effect of the phosphate substrate on drug-inhibitor binding to human purine nucleoside phosphorylase.

Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism.

Large-scale proteomics and phosphoproteomics of urinary exosomes.

Four generations of transition-state analogues for human purine nucleoside phosphorylase.

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.

Catalytic site conformations in human PNP by 19F-NMR and crystallography.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

A massively parallel pipeline to clone DNA variants and examine molecular phenotypes of human disease mutations.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

A reference map of the human binary protein interactome.

Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.

A human purine nucleoside phosphorylase deficiency caused by a single base change.

Purine nucleoside phosphorylase activity of human erythrocytes in iron deficiency anaemia.

Characterization of purine nucleoside phosphorylase from human granulocytes and its metabolism of deoxyribonucleosides.

Purine nucleoside phosphorylase. 1. Structure-function studies.

Purine nucleoside phosphorylase. 3. Reversal of purine base specificity by site-directed mutagenesis.

PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose-1-phosphate to (deoxy)inosine

PNP catalyzes the conversion of guanine and (deoxy)ribose-1-phosphate to (deoxy)guanosine

Exocytosis of secretory granule lumen proteins

Exocytosis of ficolin-rich granule lumen proteins

PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose

PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose

Defective PNP does not convert (deoxy)inosine to hypoxanthine and (deoxy)ribose

Defective PNP does not convert (deoxy)guanosine to guanine and (deoxy)ribose

PNP trimer transforms RBV to T-CONH2