Gene Ontology annotation through association of InterPro records with GO terms
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Asymmetric Notch activation specifies photoreceptors R3 and R4 and planar polarity in the Drosophila eye.
Notch-mediated segmentation and growth control of the Drosophila leg.
Composite signalling from Serrate and Delta establishes leg segments in Drosophila through Notch.
Subdividing cell populations in the developing limbs of Drosophila: do wing veins and leg segments define units of growth control?
Multiple signalling pathways establish cell fate and cell number in Drosophila malpighian tubules.
Notch signaling and the determination of appendage identity.
Spatially restricted factors cooperate with notch in the regulation of Enhancer of split genes.
The enhancer of split complex of Drosophila includes four Notch-regulated members of the bearded gene family.
Glycosyltransferase activity of Fringe modulates Notch-Delta interactions.
A model Notch response element detects Suppressor of Hairless-dependent molecular switch.
Notch signaling represses the glial fate in fly PNS.
A requirement for Notch in the genesis of a subset of glial cells in the Drosophila embryonic central nervous system which arise through asymmetric divisions.
A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters.
Delta/Notch and Boss/Sevenless signals act combinatorially to specify the Drosophila R7 photoreceptor.
fringe and Notch specify polar cell fate during Drosophila oogenesis.
Requirement of Notch in adulthood for neurological function and longevity.
Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate.
Cell proliferation, survival, and death in the Drosophila eye.
A genetic hierarchy establishes mitogenic signalling and mitotic competence in the renal tubules of Drosophila.
Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling.
Context-dependent utilization of Notch activity in Drosophila glial determination.
Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila.
Notch signaling controls lineage specification during Drosophila larval hematopoiesis.
Patterning the fly eye: the role of apoptosis.
Signal-induced transcriptional activation by Dif requires the dTRAP80 mediator module.
A Serrate-expressing signaling center controls Drosophila hematopoiesis.
Genetic control of Drosophila nerve cord development.
Myogenic cells fates are antagonized by Notch only in asymmetric lineages of the Drosophila heart, with or without cell division.
Notch steers Drosophila ISNb motor axons by regulating the Abl signaling pathway.
Vein-positioning in the Drosophila wing in response to Hh; new roles of Notch signaling.
The formation of sense organs in Drosophila: a logical approach.
Regulation of Notch signaling by a novel mechanism involving suppressor of hairless stability and carboxyl terminus-truncated notch.
Numb inhibits membrane localization of Sanpodo, a four-pass transmembrane protein, to promote asymmetric divisions in Drosophila.
A Notch/Delta-dependent relay mechanism establishes anterior-posterior polarity in Drosophila.
Phospholipid membrane composition affects EGF receptor and Notch signaling through effects on endocytosis during Drosophila development.
scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila.
Regulation of cell cycles in Drosophila development: intrinsic and extrinsic cues.
Echinoid facilitates Notch pathway signalling during Drosophila neurogenesis through functional interaction with Delta.
Growth and specification of the eye are controlled independently by Eyegone and Eyeless in Drosophila melanogaster.
Cooperation of JAK/STAT and Notch signaling in the Drosophila foregut.
Asymmetric localization and function of cell-fate determinants: a fly's view.
The mitotic-to-endocycle switch in Drosophila follicle cells is executed by Notch-dependent regulation of G1/S, G2/M and M/G1 cell-cycle transitions.
Notch signaling in Drosophila long-term memory formation.
Evidence for a fruit fly hemangioblast and similarities between lymph-gland hematopoiesis in fruit fly and mammal aorta-gonadal-mesonephros mesoderm.
Regulation of Notch signaling by Drosophila heparan sulfate 3-O sulfotransferase.
The adhesion force of Notch with Delta and the rate of Notch signaling.
Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation.
Regulation of notch endosomal sorting and signaling by Drosophila Nedd4 family proteins.
Extracellular signals responsible for spatially regulated proliferation in the differentiating Drosophila eye.
Function of the ETS transcription factor Yan in border cell migration.
Notch signaling controls proliferation through cell-autonomous and non-autonomous mechanisms in the Drosophila eye.
Influence of Notch on dorsoventral compartmentalization and actin organization in the Drosophila wing.
Sec15, a component of the exocyst, promotes notch signaling during the asymmetric division of Drosophila sensory organ precursors.
Nicastrin controls aspects of photoreceptor neuron specification and differentiation in the Drosophila eye.
Evidence that nervy, the Drosophila homolog of ETO/MTG8, promotes mechanosensory organ development by enhancing Notch signaling.
Bunched sets a boundary for Notch signaling to pattern anterior eggshell structures during Drosophila oogenesis.
Structure and Notch receptor binding of the tandem WWE domain of Deltex.
Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor.
Notch pathway repression by vestigial is required to promote indirect flight muscle differentiation in Drosophila melanogaster.
Social interactions among epithelial cells during tracheal branching morphogenesis.
An NRSF/REST-like repressor downstream of Ebi/SMRTER/Su(H) regulates eye development in Drosophila.
Border of Notch activity establishes a boundary between the two dorsal appendage tube cell types.
Spatially localized Kuzbanian required for specific activation of Notch during border cell migration.
Stem cells signal to the niche through the Notch pathway in the Drosophila ovary.
Notch and Numb are required for normal migration of peripheral glia in Drosophila.
Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts.
The PDZ protein Canoe/AF-6 links Ras-MAPK, Notch and Wingless/Wnt signaling pathways by directly interacting with Ras, Notch and Dishevelled.
Polarized exocytosis and transcytosis of Notch during its apical localization in Drosophila epithelial cells.
Notch signaling controls germline stem cell niche formation in the Drosophila ovary.
Conformational variability of the intracellular domain of Drosophila Notch and its interaction with Suppressor of Hairless.
Notch activation stimulates transient and selective binding of Su(H)/CSL to target enhancers.
Specificity and autoregulation of Notch binding by tandem WW domains in suppressor of Deltex.
Cellular behavior in the developing Drosophila pupal retina.
The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila.
Temporal switching of regulation and function of eye gone (eyg) in Drosophila eye development.
Notch signalling coordinates tissue growth and wing fate specification in Drosophila.
Notch down-regulation by endocytosis is essential for pigment cell determination and survival in the Drosophila retina.
The Drosophila cell adhesion molecule klingon is required for long-term memory formation and is regulated by Notch.
The HLH protein Extramacrochaetae is required for R7 cell and cone cell fates in the Drosophila eye.
A role for the Drosophila neurogenic genes in mesoderm differentiation.
Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell division.
On the mechanism underlying the divergent retinal and bristle defects of M8* (E(spl)D) in Drosophila.
Ligand-independent traffic of Notch buffers activated Armadillo in Drosophila.
In vivo analysis of the Notch receptor S1 cleavage.
Lineage-specific cell death in postembryonic brain development of Drosophila.
On the roles of Notch, Delta, kuzbanian, and inscuteable during the development of Drosophila embryonic neuroblast lineages.
Notch mRNA expression in Drosophila embryos is negatively regulated at the level of mRNA 3' processing.
A transient niche regulates the specification of Drosophila intestinal stem cells.
dFezf/Earmuff maintains the restricted developmental potential of intermediate neural progenitors in Drosophila.
Gene deletion screen for cardiomyopathy in adult Drosophila identifies a new notch ligand.
Dynamic intracellular distribution of Notch during activation and asymmetric cell division revealed by functional fluorescent fusion proteins.
deltex, a locus interacting with the neurogenic genes, Notch, Delta and mastermind in Drosophila melanogaster.
Noncanonical Notch function in motor axon guidance is mediated by Rac GTPase and the GEF1 domain of Trio.
How Notch establishes longitudinal axon connections between successive segments of the Drosophila CNS.
Tarsal-less peptides control Notch signalling through the Shavenbaby transcription factor.
UVRAG is required for organ rotation by regulating Notch endocytosis in Drosophila.
Structural and functional analysis of the repressor complex in the Notch signaling pathway of Drosophila melanogaster.
Insensitive is a corepressor for Suppressor of Hairless and regulates Notch signalling during neural development.
Multiple O-glucosylation sites on Notch function as a buffer against temperature-dependent loss of signaling.
Notch-mediated repression of bantam miRNA contributes to boundary formation in the Drosophila wing.
Distinct levels of Notch activity for commitment and terminal differentiation of stem cells in the adult fly intestine.
bHLH-O proteins are crucial for Drosophila neuroblast self-renewal and mediate Notch-induced overproliferation.
Drosophila midgut homeostasis involves neutral competition between symmetrically dividing intestinal stem cells.
The bHLH repressor Deadpan regulates the self-renewal and specification of Drosophila larval neural stem cells independently of Notch.
The Notch locus and the genetic circuitry involved in early Drosophila neurogenesis.
Sanpodo controls sensory organ precursor fate by directing Notch trafficking and binding γ-secretase.
Notch and PKC are involved in formation of the lateral region of the dorso-ventral axis in Drosophila embryos.
Notch-inducible hyperphosphorylated CREB and its ultradian oscillation in long-term memory formation.
A Serrate-Notch-Canoe complex mediates essential interactions between glia and neuroepithelial cells during Drosophila optic lobe development.
An unexpected link between notch signaling and ROS in restricting the differentiation of hematopoietic progenitors in Drosophila.
Compensatory flux changes within an endocytic trafficking network maintain thermal robustness of Notch signaling.
Uninflatable and Notch control the targeting of Sara endosomes during asymmetric division.
Integration of UPRER and oxidative stress signaling in the control of intestinal stem cell proliferation.
The bHLH-PAS transcription factor dysfusion regulates tarsal joint formation in response to Notch activity during drosophila leg development.
A fluorescent tagging approach in Drosophila reveals late endosomal trafficking of Notch and Sanpodo.
Notch signaling mediates the age-associated decrease in adhesion of germline stem cells to the niche.
Thermodynamic binding analysis of Notch transcription complexes from Drosophila melanogaster.
A large-scale in vivo RNAi screen to identify genes involved in Notch-mediated follicle cell differentiation and cell cycle switches.
Notch stimulates growth by direct regulation of genes involved in the control of glycolysis and the tricarboxylic acid cycle.
The sexual identity of adult intestinal stem cells controls organ size and plasticity.
Dual Roles of O-Glucose Glycans Redundant with Monosaccharide O-Fucose on Notch in Notch Trafficking.
Notch maintains Drosophila type II neuroblasts by suppressing expression of the Fez transcription factor Earmuff.
Notch is required for successive cell decisions in the developing Drosophila retina.
Prevention of medulla neuron dedifferentiation by Nerfin-1 requires inhibition of Notch activity.
A late role for a subset of neurogenic genes to limit sensory precursor recruitments in Drosophila embryos.
The Super Elongation Complex Drives Neural Stem Cell Fate Commitment.
The bantam microRNA acts through Numb to exert cell growth control and feedback regulation of Notch in tumor-forming stem cells in the Drosophila brain.
Notch-dependent epithelial fold determines boundary formation between developmental fields in the Drosophila antenna.
bHLH-O proteins balance the self-renewal and differentiation of Drosophila neural stem cells by regulating Earmuff expression.
Ubiquitylation-independent activation of Notch signalling by Delta.
Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate.
Epsin-Dependent Ligand Endocytosis Activates Notch by Force.
A Phyllopod-Mediated Feedback Loop Promotes Intestinal Stem Cell Enteroendocrine Commitment in Drosophila.
AKAP200 promotes Notch stability by protecting it from Cbl/lysosome-mediated degradation in Drosophila melanogaster.
Activation of the Notch Signaling Pathway In Vivo Elicits Changes in CSL Nuclear Dynamics.
A population of adult satellite-like cells in Drosophila is maintained through a switch in RNA-isoforms.
Regulation of Notch signaling by the chromatin-modeling protein Hat-trick.
Ubiquitylation is required for the incorporation of the Notch receptor into intraluminal vesicles to prevent prolonged and ligand-independent activation of the pathway.
Notch-dependent Abl signaling regulates cell motility during ommatidial rotation in Drosophila.
Kuzbanian expression levels dictate Notch signaling outcomes via interplay between cis- and trans-Delta.
Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats.
The suppressor of hairless protein participates in notch receptor signaling.
Cytosolic interaction between deltex and Notch ankyrin repeats implicates deltex in the Notch signaling pathway.
Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo.
An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye.
Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation.
Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H).
Numb antagonizes Notch signaling to specify sibling neuron cell fates.
The neurogenic genes egghead and brainiac define a novel signaling pathway essential for epithelial morphogenesis during Drosophila oogenesis.
Cell proliferation control by Notch signaling in Drosophila development.
Notch signalling mediates segmentation of the Drosophila leg.
Processing of the notch ligand delta by the metalloprotease Kuzbanian.
Mastermind acts downstream of notch to specify neuronal cell fates in the Drosophila central nervous system.
Drosophila NICD traffics to nucleus
Endoplasmic reticulum calcium ATPases positively regulate Notch precursor trafficking
Rab6 positively regulates Notch trafficking through Golgi
Deltex recruits Kurtz arrestin to Notch
Serrate binds Notch in cis
DL/SER is ubiquitinated by E3 ubiquitination ligases (NEUR/MIB1)
Kurtz promotes ubiquitination of Notch
N deep research / notes (N-deep-research-falcon.md)