Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Automatic Gene Ontology annotation based on Rhea mapping
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
The isolation and characterization of a cDNA encoding phospholipid-specific inositol polyphosphate 5-phosphatase.
INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse.
Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies.
Architecture of the human interactome defines protein communities and disease networks.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
A central chaperone-like role for 14-3-3 proteins in human cells.
Synthesis of PIPs at the Golgi membrane
PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane
INPP5E translocates to the primary cilium
PDE6D dissociates from ARL13B:INPP5E
A homozygous PDE6D mutation in Joubert syndrome impairs targeting of farnesylated INPP5E protein to the primary cilium.
Modulation of Ciliary Phosphoinositide Content Regulates Trafficking and Sonic Hedgehog Signaling Output.
Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling.
INPP5E-deep-research-falcon.md
UniProtKB Q9NRR6 (INPP5E) entry
Regulation of IGF-1/PI3K/Akt signalling by the phosphoinositide phosphatase pharbin.