Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Evolutionary change within a bipotential switch shaped the sperm/oocyte decision in hermaphroditic nematodes.
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Cbr-TRR-1 acts through the TRA-1 transcription factor to activate Cbr-fog-3 and to control the germline sperm/oocyte fate decision; reducing trr-1 activity produces a feminized (Fog) germ line.
"TRR-1 works through TRA-1, both to activate Cbr-fog-3 and to control the sperm/oocyte decision"