Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Towards a proteome-scale map of the human protein-protein interaction network.
An empirical framework for binary interactome mapping.
Protein interactome reveals converging molecular pathways among autism disorders.
Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical β-propeller domain.
Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human.
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Mouse Eml1 perturbation alters progenitor positioning, cycling and spindle orientation, while human EML1 variants are associated with severe cortical malformations.
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Tagged Eml1 is reported at metaphase spindle poles and the late-mitotic interzonal region in progenitor cultures; endogenous localization was not analyzed.
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.
Microtubule association of EML proteins and the EML4-ALK variant 3 oncoprotein require an N-terminal trimerization domain.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Isolation of a novel human homologue of the gene coding for echinoderm microtubule-associated protein (EMAP) from the Usher syndrome type 1a locus at 14q32.
EML1: reproducible source, sequence and database evidence