Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Gene Ontology annotation of human sequence-specific DNA binding transcription factors (DbTFs) based on the TFClass database
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia.
The Papillomavirus E2 protein binds to and synergizes with C/EBP factors involved in keratinocyte differentiation.
Transcriptional regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein alpha and hepatocyte nuclear factor-3 gamma.
The CCAAT enhancer-binding protein alpha (C/EBPalpha) requires a SWI/SNF complex for proliferation arrest.
Roles of CHOP/GADD153 in endoplasmic reticulum stress.
Liver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP alpha growth inhibitory activity.
Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription factors C/EBP, DBP, and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene (HGF).
Signal transducers and activators of transcription 3 augments the transcriptional activity of CCAAT/enhancer-binding protein alpha in granulocyte colony-stimulating factor signaling pathway.
In prostate cancer cells the interaction of C/EBPalpha with Ku70, Ku80, and poly(ADP-ribose) polymerase-1 increases sensitivity to DNA damage.
STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation.
Homeodomain transcription factor CDX1 is required for the transcriptional induction of PPARgamma in intestinal cell differentiation.
Nucleolar retention of a translational C/EBPalpha isoform stimulates rDNA transcription and cell size.
Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays.
Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis.
Networks of bZIP protein-protein interactions diversified over a billion years of evolution.
Interleukin (IL)-32β-mediated CCAAT/enhancer-binding protein α (C/EBPα) phosphorylation by protein kinase Cδ (PKCδ) abrogates the inhibitory effect of C/EBPα on IL-10 production.
Hepatitis C virus-induced changes in microRNA 107 (miRNA-107) and miRNA-449a modulate CCL2 by targeting the interleukin-6 receptor complex in hepatitis.
EVI2B is a C/EBPα target gene required for granulocytic differentiation and functionality of hematopoietic progenitors.
Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Obesity caused by an OVOL2 mutation reveals dual roles of OVOL2 in promoting thermogenesis and limiting white adipogenesis.
Mapping adipocyte interactome networks by HaloTag-enrichment-mass spectrometry.
NF-kappa B and C/EBP transcription factor families synergistically function in mouse serum amyloid A gene expression induced by inflammatory cytokines.
The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression.
Stress-induced binding of the transcriptional factor CHOP to a novel DNA control element.
Transcription factor C/EBPalpha: novel sites of expression and cloning of the human gene.
SPI1 (PU.1), CEBPA and DEK bind the promoter of the CSF3R (G-CSFR) gene
CEBPA binds the promoter of the KLF5 gene
Suppression of C/EBPalpha expression in periportal hepatoblasts may stimulate biliary cell differentiation through increased Hnf6 and Hnf1b expression.
C/EBPalpha is required for lung maturation at birth.
Increased hepatic cell proliferation and lung abnormalities in mice deficient in CCAAT/enhancer binding protein alpha.
Distinct C/EBPalpha motifs regulate lipogenic and gluconeogenic gene expression in vivo.
MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α-PU.1 pathway.
SUCNR1 signaling in adipocytes controls energy metabolism by modulating circadian clock and leptin expression.
The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors.
E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo.
C/EBPalpha triggers proteasome-dependent degradation of cdk4 during growth arrest.
CEBPA source evidence: exact interaction records, bZIP target measurements and ortholog links
C/EBPalpha arrests cell proliferation through direct inhibition of Cdk2 and Cdk4.
The proline-histidine-rich CDK2/CDK4 interaction region of C/EBPalpha is dispensable for C/EBPalpha-mediated growth regulation in vivo.