Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features

Automatic assignment of GO terms using logical inference, based on on inter-ontology links

Combined Automated Annotation using Multiple IEA Methods

UniProt record for horse SIRT5 (A0A9L0T9B1)

Comparison of horse SIRT5 gene models with human SIRT5

Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins.

Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5.

The first identification of lysine malonylation substrates and its regulatory enzyme.

Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase.

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

SIRT5 desuccinylates and activates SOD1 to eliminate ROS.

Lysine glutarylation is a protein posttranslational modification regulated by SIRT5.