Gene Ontology annotation through association of InterPro records with GO terms

Combined Automated Annotation using Multiple IEA Methods

Ethylmalonyl coenzyme A mutase operates as a metabolic control point in Methylobacterium extorquens AM1

Ecm catalyzes the transformation of (2R)-ethylmalonyl-CoA to (2S)-methylsuccinyl-CoA
Ecm requires adenosylcobalamin as a cofactor
Ecm acts as a regulatory metabolic control point in the ethylmalonyl-CoA pathway

Molecular characterization of a chromosomal region involved in the oxidation of acetyl-CoA to glyoxylate in the isocitrate-lyase-negative methylotroph Methylobacterium extorquens AM1.

ecm mutants lose the ability to grow on C1 and C2 compounds
Growth is restored by addition of glyoxylate or glycolate

PMID:8868443

A protein having similarity with methylmalonyl-CoA mutase is required for the assimilation of methanol and ethanol by Methylobacterium extorquens AM1.

Ecm is required for methanol and ethanol assimilation in M. extorquens AM1