GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
PMID:11063725
The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG.
PMID:12397061
The anti-apoptotic function of Hsp70 in the interferon-inducible double-stranded RNA-dependent protein kinase-mediated death signaling pathway requires the Fanconi anemia protein, FANCC.
PMID:12649160
Fanconi anemia protein complex: mapping protein interactions in the yeast 2- and 3-hybrid systems.
PMID:1574115
Cloning of cDNAs for Fanconi's anaemia by functional complementation.
PMID:19965384
The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair.
PMID:20347428
A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability.
PMID:22266823
Regulation of Rev1 by the Fanconi anemia core complex.
PMID:22343915
FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway.
PMID:24412244
Charting the molecular links between driver and susceptibility genes in colorectal cancer.
PMID:26871637
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
PMID:35512704
Systematic discovery of mutation-directed neo-protein-protein interactions in cancer.
PMID:9787138
Abnormal microsomal detoxification implicated in Fanconi anemia group C by interaction of the FAC protein with NADPH cytochrome P450 reductase.
PMID:9398857
The Fanconi anaemia proteins, FAA and FAC, interact to form a nuclear complex.
PMID:9596688
Molecular chaperone GRP94 binds to the Fanconi anemia group C protein and regulates its intracellular expression.
PMID:11520787
The Fanconi anemia complementation group C gene product: structural evidence of multifunctionality.
Reactome:R-HSA-6785126
FA core complex assembles at DNA interstrand crosslinks (ICLs)
Reactome:R-HSA-6785342
FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex
Reactome:R-HSA-6785361
Monoubiquitination of FANCD2:FANCI
Reactome:R-HSA-6785732
DNA nucleases bind monoubiquitinated ID2 complex
Reactome:R-HSA-6785986
DNA nucleases unhook the interstrand crosslink (ICL)
Reactome:R-HSA-6786155
POLN binds ICL-DNA
Reactome:R-HSA-6786166
Translesion synthesis across unhooked ICL by POLN
Reactome:R-HSA-6786171
FANCD2 deubiquitination by USP1:WDR48
Reactome:R-HSA-6788385
The complex of ATR and ATRIP is recruited to ICL-DNA
Reactome:R-HSA-6788392
ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA
Reactome:R-HSA-6806425
TP53 stimulates FANCC expression
Reactome:R-HSA-9835411
FA core complex:HSP70s binds PKR