FAA3 (YIL009W; UniProt P39002) notes
- Long-chain acyl-CoA synthetase preferring C16/C18 cis-9 acids PMID:8206942; ~100-fold lower myristoyl-CoA synthetase activity than Faa1p/Faa2p PMID:8206942.
- Plasma membrane / cell periphery (GFP) [PMID:14562095; UniProt:P39002]. Interacts with Frk1 [UniProt:P39002].
- No assigned role in uptake or beta-oxidation PMID:7962057.
Pathway-context observations
- YeastCyc attaches FAA3 to the fatty-acid oxidation activation step without yeast evidence (paralog/superfamily attachment). FAO RCA and cytosol RCA marked over-annotated; LD IBA over-annotated (Faa3p absent from LD proteomes that recover Faa1/Faa4/Fat1).