PFK1 notes (P16861, YGR240C) — PFK alpha subunit

• alpha4beta4 PFK, EC 2.7.1.11 [UniProt:P16861 "SUBUNIT: Heterooctamer of 4 alpha and 4 beta chains."]; activity needs both subunits PMID:3007939.
• Double mutant glucose-negative PMID:2965996; activators AMP/F2,6BP PMID:6219673.
• V-ATPase link: co-IP and pH defects PMID:24860096; proton transport normal in pfk1 PMID:24860096.
• RNA binding shared with Pfk2 PMID:41816908, but NOT ribosome-bound PMID:41816908.

Decisions: REMOVE ribosome binding IDA+IEA (contradicted in full text of the cited paper), protein binding x6, bifid n/a; contributes_to proton-transporting ATPase and proton transport MARK_AS_OVER_ANNOTATED; RNA-binding rows KEEP_AS_NON_CORE.