Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Combined Automated Annotation using Multiple IEA Methods
KGF and FGF-10 stimulate liquid secretion in human fetal lung.
alpha2-macroglobulin modulates the immunoregulatory function of the lipocalin placental protein 14.
Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations.
Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene.
Fibroblast growth factors 7 and 10 are expressed in the human embryonic pancreatic mesenchyme and promote the proliferation of embryonic pancreatic epithelial cells.
Cortactin involvement in the keratinocyte growth factor and fibroblast growth factor 10 promotion of migration and cortical actin assembly in human keratinocytes.
Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth.
Purification and characterization of a newly identified growth factor specific for epithelial cells.
The function of KGF in morphogenesis of epithelium and reepithelialization of wounds.
Receptor specificity of the fibroblast growth factor family.
FGF-10 is a chemotactic factor for distal epithelial buds during lung development.
PI3K-containing complexes phosphorylate PIP2 to PIP3
Autocatalytic phosphorylation of FGFR2b
FGFR2c mutants bind an expanded range of ligands
FGFR2b mutants bind an expanded range of ligands
Autocatalytic phosphorylation of FGFR2c mutants with enhanced ligand binding
Autocatalytic phosphorylation of FGFR2b mutants with enhanced ligand binding
FP-1039 acts as a ligand-trap for FGFR2b-binding ligands in endometrial cancer
Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors
PI3K phosphorylates PIP2 to PIP3
PI3K inhibitors block PI3K catalytic activity
Activated FGFR2 phosphorylates PLCG1
p-4Y-PLCG1 dissociates from activated FGFR2
Activated FGFR2 binds PLCG1
Activated FGFR2 phosphorylates FRS2
Activated FGFR2 binds FRS2
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange
Activated FGFR2 binds SHC1
Activated FGFR2:p-SHC1 binds GRB2:SOS1
Activated FGFR2 phosphorylates SHC1
Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2
Activated FGFR2 binds FRS3
Activated FGFR2 phosphorylates FRS3
Activated FGFR2 phosphorylates PPTN11
Activated FGFR2:p-FRS bind to PPTN11
Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA
Activated FGFR2:pFRS binds GRB2:SOS1
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange
Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1
Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA
CBL ubiquitinates FRS2 and FGFR2
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3
FGFR2-associated PI3K phosphorylates PIP2 to PIP3
p-CBL:GRB2 binds p-FRS2:activated FGFR2
p-4Y-PLCG1 dissociates from activated FGFR2 mutants
Activated FGFR2 mutants:p-FRS2 binds GRB2-SOS1
Activated FGFR2 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange
Activated FGFR2 mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA
Activated FGFR2 mutants phosphorylate FRS2
Activated FGFR2 mutants phosphorylate PLCG1
Activated FGFR2 mutants:p-FRS2 binds GRB2:GAB1:PIK3R1
Activated FGFR2 mutant-associated PI3K phosphorylates PIP2 to PIP3
Activated FGFR2 mutants bind FRS2
Activated FGFR2 mutants bind PLCG1
RAS GEFs promote RAS nucleotide exchange
The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair.
Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family.
Distinct FGFs promote differentiation of excitatory and inhibitory synapses.
Fibroblast growth factor 22 and its potential role during skin development and repair.
Elf5 is an epithelium-specific, fibroblast growth factor-sensitive transcription factor in the embryonic lung.
UniProt entry P21781 (FGF7_HUMAN)
Deep research report on FGF7 (falcon)