Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Nuclear import of activated D-ERK by DIM-7, an importin family member encoded by the gene moleskin.
MAP kinase subcellular localization controls both pattern and proliferation in the developing Drosophila wing.
smoothened and thickveins regulate Moleskin/Importin 7-mediated MAP kinase signaling in the developing Drosophila eye.
A genetic screen in Drosophila for genes interacting with senseless during neuronal development identifies the importin moleskin.
Nuclear localization of the ERK MAP kinase mediated by Drosophila alphaPS2betaPS integrin and importin-7.
Identification and characterization of Drosophila Snurportin reveals a role for the import receptor Moleskin/importin-7 in snRNP biogenesis.
Subcellular localisations of the CPTI collection of YFP-tagged proteins in Drosophila embryos.
Msk is required for nuclear import of TGF-{beta}/BMP-activated Smads.
Mechanical control of nuclear import by Importin-7 is regulated by its dominant cargo YAP.
Moleskin is essential for the formation of the myotendinous junction in Drosophila.
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Msk is enriched at muscle attachment sites and is required in the muscle for muscle-tendon attachment, signalling to tendon cells through Vein-EGFR.
"Msk protein is enriched at muscle attachment sites in late embryogenesis and msk mutant embryos exhibit a failure in muscle-tendon cell attachment."
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Activated MAPK or the EGFR ligand Vein rescues msk muscle attachment defects.
"Moreover, muscle attachment defects due to loss of Msk are rescued by an activated form of MAPK or the secreted epidermal growth factor receptor (Egfr) ligand Vein."
Drosophila importin-7 functions upstream of the Elmo signaling module to mediate the formation and stability of muscle attachments.
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Dim7/Msk acts upstream of Elmo-Mbc-Rac in forming embryonic muscle attachment sites.
"We show that Drosophila importin-7 (Dim7) is an upstream regulator of the conserved Elmo-Mbc→Rac signaling pathway in the formation of embryonic muscle attachment sites (MASs)."
FlyBase gene description for msk (DROME)