UniProt entry for rat Arrb2 (Beta-arrestin-2)

Manual literature synthesis for rat Arrb2 (beta-arrestin-2, UniProt P29067)

Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Electronic Gene Ontology annotations created by ARBA machine learning models

RGD ISO annotations to rat from other mammalian species

A G protein-coupled receptor kinase induces Xenopus oocyte maturation.

Differential regulation of beta-arrestin 1 and beta-arrestin 2 gene expression in rat brain by morphine.

Loss of intracellular dystrophin: a potential mechanism for myocardial reperfusion injury.

Heterodimerization of V1a and V2 vasopressin receptors determines the interaction with beta-arrestin and their trafficking patterns.

Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family.

c-Src regulates clathrin adapter protein 2 interaction with beta-arrestin and the angiotensin II type 1 receptor during clathrin- mediated internalization.

Partial purification of a bone-resorbing factor elaborated from human allogeneic cultures.

An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior.

Morphine promotes rapid, arrestin-dependent endocytosis of mu-opioid receptors in striatal neurons.

G protein-coupled receptor kinase 2 and beta-arrestins are recruited to FSH receptor in stimulated rat primary Sertoli cells.

Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2.

beta-arrestin 2 oligomerization controls the Mdm2-dependent inhibition of p53.

A beta-arrestin 2 signaling complex mediates lithium action on behavior.

Different internalization properties of the alpha1a- and alpha1b-adrenergic receptor subtypes: the potential role of receptor interaction with beta-arrestins and AP50.

Targeting of beta-arrestin2 to the centrosome and primary cilium: role in cell proliferation control.

Kappa opioids promote the proliferation of astrocytes via Gbetagamma and beta-arrestin 2-dependent MAPK-mediated pathways.

{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation.

Dopamine promotes striatal neuronal apoptotic death via ERK signaling cascades.

Independent beta-arrestin2 and Gq/protein kinase Czeta pathways for ERK stimulated by angiotensin type 1A receptors in vascular smooth muscle cells converge on transactivation of the epidermal growth factor receptor.

Vascular hyporesponsiveness to angiotensin II in rats with CCl(4)-induced liver cirrhosis.

Differences in the C-terminus contribute to variations in trafficking between rat and human 5-HT(2A) receptor isoforms: identification of a primate-specific tripeptide ASK motif that confers GRK-2 and beta arrestin-2 interactions.

Arresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4.

{Beta}-blocker drugs mediate calcium signaling in native central nervous system neurons by {beta}-arrestin-biased agonism.

Antinociceptive potentiation and attenuation of tolerance by intrathecal β-arrestin 2 small interfering RNA in rats.

Α-arrestin 1 (ARRDC1) and β-arrestins cooperate to mediate Notch degradation in mammals.

PAF enhances MMP-2 production in rat aortic VSMCs via a β-arrestin2-dependent ERK signaling pathway.

Reactive oxygen species are involved in regulating hypocontractility of mesenteric artery to norepinephrine in cirrhotic rats with portal hypertension.

Differential regulation of endosomal GPCR/β-arrestin complexes and trafficking by MAPK.

Beta-arrestin1 and 2 differently modulate metabotropic glutamate receptor 7 signaling in rat developmental sevoflurane-induced neuronal apoptosis.

β-Arrestin-biased AT1R stimulation promotes extracellular matrix synthesis in renal fibrosis.

Disrupted circadian expression of β-arrestin 2 affects reward-related µ-opioid receptor function in alcohol dependence.