Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Electronic Gene Ontology annotations created by ARBA machine learning models
A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.
Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis.
Towards a proteome-scale map of the human protein-protein interaction network.
h2-Calponin is regulated by mechanical tension and modifies the function of actin cytoskeleton.
Large-scale mapping of human protein-protein interactions by mass spectrometry.
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Next-generation sequencing to generate interactome datasets.
Human respiratory syncytial virus N, P and M protein interactions in HEK-293T cells.
A proteome-scale map of the human interactome network.
Widespread macromolecular interaction perturbations in human genetic disorders.
Quantitative interaction proteomics of neurodegenerative disease proteins.
Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.
Tissue-specific expression of the human tropomyosin gene involved in the generation of the trk oncogene.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
A reference map of the human binary protein interactome.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Organization of the hTMnm gene. Implications for the evolution of muscle and non-muscle tropomyosins.
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
Autosomal dominantly inherited myopathy likely caused by the TNNT1 variant p.(Asp65Ala).
Multimodal cell maps as a foundation for structural and functional genomics.
Release Of ADP From Myosin
Release Of ADP From Myosin
Ligand-independent dimerization of ALK fusions
Autophosphorylation of ALK fusions
Falcon deep research on TPM3 function
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TPM3 is an actin-filament binding coiled-coil tropomyosin whose isoforms stabilize and regulate distinct actin filament populations.
"Falcon report summarizes TPM3 as an actin-binding coiled-coil dimer that polymerizes along F-actin to stabilize filaments and regulate access of myosin and other actin-binding proteins."
UniProt record for human TPM3