"The Bacillus subtilis spoVD gene has been cloned and sequenced. It encodes a 71,262 Da protein with extensive sequence similarity to penicillin-binding proteins from various organisms"

"SpoVD synthesis probably occurs only in the mother cell since both sigma E and SpoIIID are thought to be specific to this cell type"

"Expression of spoVD in E. coli leads to the synthesis of a membrane-associated protein of the size expected for SpoVD, which can bind labelled penicillin"

"insertional disruption of the spoVD gene has no effect on vegetative growth or division"

"spoVD seems instead to have a specialized role in the morphogenesis of the spore cortex, which is a modified form of peptidoglycan"

"SpoVD, a nonessential class B penicillin binding protein"

"we have taken advantage of the peptidoglycan synthesis that occurs during sporulation in Bacillus subtilis to examine the interactions between SpoVE, a nonessential, sporulation-specific homolog of the well-conserved and essential SEDS (shape elongation, division, and sporulation) proteins, and SpoVD, a nonessential class B penicillin binding protein"

"localization of SpoVD is dependent on SpoVE"

"a loss-of-function point mutation in either part of the fusion resulted in loss of function of the entire fusion"

"fluorescence resonance energy transfer experiments indicated that SpoVE and SpoVD interact, and co-affinity purification in Escherichia coli demonstrated that this interaction is direct"

"In B. subtilis, SpoVE forms a complex with the sporulation-specific bPBP SpoVD to synthesize a thick protective PG layer known as the cortex during sporulation"

"the genes present in the dcw cluster of sporulating Firmicutes likely code for SpoVE and SpoVD, respectively, rather than the canonical cell division proteins FtsW and FtsI"

"we observed that C. difficile SpoVD interacts with FtsL and FtsQ, suggesting that the ternary sub-complex likely directly regulates the activity of SpoVE-SpoVD"