SadC reciprocally influences biofilm formation and swarming motility via modulation of exopolysaccharide production and flagellar function.
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SadC is an inner-membrane DGC; the deletion is biofilm-defective and hyperswarms, while multicopy sadC promotes sessility.
"Deletion of the sadC gene results in a strain that is defective in biofilm formation and a hyperswarmer, while multicopy expression of this gene promotes sessility."
Synergistic interaction of glyceraldehydes-3-phosphate dehydrogenase and ArsJ, a novel organoarsenical efflux permease, confers arsenate resistance.
Cyclic-di-GMP regulates lipopolysaccharide modification and contributes to Pseudomonas aeruginosa immune evasion.
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WarA, a c-di-GMP-binding methyltransferase, is a SadC partner.
"Here, we identify an unrecognized SadC partner, WarA"
Gene Ontology annotation based on Enzyme Commission mapping
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt