GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
GO_REF:0000121
RGD ISO annotations to rat from other mammalian species
PMID:10891587
Occurrence of a transcription factor, signal transducer and activators of transcription 3 (Stat3), in the postsynaptic density of the rat brain.
PMID:14674010
Chemokine receptor expression and in vivo signaling pathways in the joints of rats with adjuvant-induced arthritis.
PMID:16055727
Signal regulatory protein alpha ligation induces macrophage nitric oxide production through JAK/STAT- and phosphatidylinositol 3-kinase/Rac1/NAPDH oxidase/H2O2-dependent pathways.
PMID:16527988
Novel role for STAT-5B in the regulation of Hsp27-FGF-2 axis facilitating thrombin-induced vascular smooth muscle cell growth and motility.
PMID:16648019
Peptide YY attenuates STAT1 and STAT3 activation induced by TNF-alpha in acinar cell line AR42J.
PMID:17911393
Signal transducer and activator of transcription 3-regulated sarcoendoplasmic reticulum Ca2+-ATPase 2 expression by prolactin and glucocorticoids is involved in the adaptation of insulin secretory response during the peripartum period.
PMID:17916759
Protective effects of estradiol on ethanol-induced bone loss involve inhibition of reactive oxygen species generation in osteoblasts and downstream activation of the extracellular signal-regulated kinase/signal transducer and activator of transcription 3/receptor activator of nuclear factor-kappaB ligand signaling cascade.
PMID:17954917
ephrinB1 signals from the cell surface to the nucleus by recruitment of STAT3.
PMID:18270592
Prevention of hypovolemic circulatory collapse by IL-6 activated Stat3.
PMID:19414010
JANEX-1, a JAK3 inhibitor, protects pancreatic islets from cytokine toxicity through downregulation of NF-kappaB activation and the JAK/STAT pathway.
PMID:19450559
STAT3 deletion sensitizes cells to oxidative stress.
PMID:19538478
Cross-talk between calcineurin/NFAT and Jak/STAT signalling induces cardioprotective alphaB-crystallin gene expression in response to hypertrophic stimuli.
PMID:20155810
Association of the glucocorticoid receptor with STAT3, C/EBPbeta, and the hormone-responsive element within the rat haptoglobin gene promoter during the acute phase response.
PMID:22284190
The Jak/STAT pathway is involved in synaptic plasticity.
PMID:23271731
The import of the transcription factor STAT3 into mitochondria depends on GRIM-19, a component of the electron transport chain.
PMID:23590160
The STAT3 inhibitor stattic impairs cardiomyocyte mitochondrial function through increased reactive oxygen species formation.
PMID:23608221
Multiple signaling pathways mediate ghrelin-induced proliferation of hippocampal neural stem cells.
PMID:23869758
Interleukin-6-induced satellite cell proliferation is regulated by induction of the JAK2/STAT3 signalling pathway through cyclin D1 targeting.
PMID:23884942
Survivin Is a transcriptional target of STAT3 critical to estradiol neuroprotection in global ischemia.
PMID:29702085
TNF-α-sensitive brain pericytes activate microglia by releasing IL-6 through cooperation between IκB-NFκB and JAK-STAT3 pathways.
PMID:38602915
IL-6/gp130 signaling in CD4(+) T cells drives the pathogenesis of pulmonary hypertension.
PMID:8530402
Transcription factors Stat3 and Stat5b are present in rat liver nuclei late in an acute phase response and bind interleukin-6 response elements.
Reactome:R-RNO-198717
STAT3 activation
file:rat/Stat3/Stat3-uniprot.txt
UniProt entry for rat Stat3 (P52631)
file:rat/Stat3/Stat3-deep-research-manual.md
Manual literature synthesis for rat Stat3