Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Electronic Gene Ontology annotations created by ARBA machine learning models

Identification of the human and bovine ATP:Cob(I)alamin adenosyltransferase cDNAs based on complementation of a bacterial mutant.

Spectroscopic evidence for the formation of a four-coordinate Co2+ cobalamin species upon binding to the human ATP:cobalamin adenosyltransferase.

Widespread macromolecular interaction perturbations in human genetic disorders.

Protein destabilization and loss of protein-protein interaction are fundamental mechanisms in cblA-type methylmalonic aciduria.

Sacrificial Cobalt-Carbon Bond Homolysis in Coenzyme B(12) as a Cofactor Conservation Strategy.

Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.

Redox-Linked Coordination Chemistry Directs Vitamin B(12) Trafficking.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

Multimodal cell maps as a foundation for structural and functional genomics.

Structure of ATP-bound human ATP:cobalamin adenosyltransferase.

MMAB adenosylates cob(I)alamin

Defective MMAB does not transfer adenosyl group from ATP to B12s

Cobalamin (Cbl) metabolism