Reviewed every one of the 20 original annotations and all core functions using the review and annotation-reviewer workflows. Machine payloads, row order, evidence codes, qualifiers, source identifiers and WITH/FROM values were preserved. No NEW rows were added.
Purified-protein PMID:20450881 demonstrates FAD-associated proline dehydrogenase and strong CoQ1 electron acceptance; low oxidase turnover does not make oxygen the obligatory immediate acceptor. ETF knockout growth tests support dispensability of ETF for the tested yeast proline use. PMID:3125423 demonstrates mitochondrial targeting and explicitly shows high expression in respiratory-deficient cells; the old assertion that expression requires a functional respiratory chain is corrected. Oxygen-regulated transcription is distinct from respiratory coupling of proline utilization. Matrix assignment remains curated/comparative; membrane topology is not newly measured here. PMID:32978391 measures mitochondrial proline uptake and metabolite flux in Put6/Put7 mutants but does not identify those factors as the carrier. No transport activity is assigned to Put1.
Normal publication caching passed. Genuine Falcon research with Perplexity-lite fallback was attempted for this gene; authentication/quota errors prevented a report. Manual source review is recorded here, with no fabricated provider-named research file. Abstract-only and bibliographic-only access are distinguished from full text; unknown target supplementary details are not treated as a contradiction. Logs are under .cache/module-audit-logs/arginase-yeast-PUT1-*.
The initial focused validation passed. Record sections are backfilled, and final schema/term/reference validation, rendering and helper-history checks are recorded in the same log directory. Actions: ACCEPT 17, KEEP_AS_NON_CORE 1, REMOVE 2.