Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG.
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis.
Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking.
Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase.
Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages.
Network organization of the human autophagy system.
A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic.
The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression.
The role of ESCRT proteins in fusion events involving lysosomes, endosomes and autophagosomes.
UV irradiation resistance-associated gene suppresses apoptosis by interfering with BAX activation.
Inhibition of autophagy by TAB2 and TAB3.
Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC.
Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex.
A dual role for UVRAG in maintaining chromosomal stability independent of autophagy.
Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism.
EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance.
PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex.
The HOPS complex mediates autophagosome-lysosome fusion through interaction with syntaxin 17.
NRBF2 regulates macroautophagy as a component of Vps34 Complex I.
NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity.
Architecture and dynamics of the autophagic phosphatidylinositol 3-kinase complex.
A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Pacer Mediates the Function of Class III PI3K and HOPS Complexes in Autophagosome Maturation by Engaging Stx17.
Beclin1 antagonizes LAPTM4B-mediated EGFR overactivation in gastric cancer cells.
A reference map of the human binary protein interactome.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
ORF3a-Mediated Incomplete Autophagy Facilitates Severe Acute Respiratory Syndrome Coronavirus-2 Replication.
Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.
Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complex.
Molecular cloning of a novel human gene encoding a 63-kDa protein and its sublocalization within the 11q13 locus.
SARS-CoV-2 3a binds to UVRAG
Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG.
UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs.
mTORC1 phosphorylates UVRAG to negatively regulate autophagosome and endosome maturation.
UniProtKB record for human UVRAG