BIN2 (ASK7/SK21; At4g18710, UniProtKB:Q39011) curation notes

Session 2026-10-05/06 (brassinosteroid_signaling module curation).

• Symbol lookup BIN2 first returned an unreviewed TrEMBL entry (F4JRM5, 274 aa fragment); refetched by accession Q39011 (KSG7_ARATH, Shaggy-related protein kinase eta = ASK7 = AtSK21 = BIN2 = DWF12 = UCU1). gene_symbol set to BIN2.
• Falcon deep research attempted; HTTP 402, no report.
• GSK3/SHAGGY kinase, negative regulator PMID:11847343
• Substrates BZR1 PMID:12114546, BES1 PMID:12007405, YDA PMID:22307275, SPCH PMID:22466366, ARF2 PMID:18599455, EGL3/TTG1 PMID:24771765, RAPTOR1B PMID:36151786.
• Inactivation: BSU1 dephosphorylation of pTyr200 PMID:19734888; KIB1-mediated degradation PMID:28575660; proteasome PMID:18726001.
• GO:0009729 detection of BR stimulus (IMP) -> MODIFY to GO:1900458 (detection is the receptor step).
• Many protein-binding IPIs: kinase partners -> GO:0019901; substrates/scaffolds -> REMOVE (uninformative).