Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Electronic Gene Ontology annotations created by ARBA machine learning models
DmGEN, a novel RAD2 family endo-exonuclease from Drosophila melanogaster.
DmGEN shows a flap endonuclease activity, cleaving the blocked-flap structure and model replication fork.
A genetic screen for DNA double-strand break repair mutations in Drosophila.
Three structure-selective endonucleases are essential in the absence of BLM helicase in Drosophila.
Substrate preference of Gen endonucleases highlights the importance of branched structures as DNA damage repair intermediates.
Drosophila FANCM helicase prevents spontaneous mitotic crossovers generated by the MUS81 and SLX1 nucleases.
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Gen is required together with MUS81 or SLX1 for viability in Fancm mutants; Gen is one of three putative mitotic HJ resolvases.
"although simultaneous loss of GEN and either of the others is lethal in Fancm mutants"
Manual literature review for Gen
FlyBase gene description for Gen (DROME)