Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Network organization of the human autophagy system.

Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells.

ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy.

A proteome-scale map of the human interactome network.

Widespread macromolecular interaction perturbations in human genetic disorders.

FUNDC1 regulates mitochondrial dynamics at the ER-mitochondrial contact site under hypoxic conditions.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.

Loss of UCHL1 rescues the defects related to Parkinson's disease by suppressing glycolysis.

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

FUNDC1 collaborates with PINK1 in regulating mitochondrial Fission and compensating for PINK1 deficiency.

FUNDC1 is phosphorylated by CK2

p-S13-FUNDC1 is dephosphorylated by PGAM5

p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18

FUNDC1 is phosphorylated by ULK1 at Ser17

LC3 binds the autophagosome membrane Atg5-Atg12 complex

Phosphorylated FUNDC1 links damaged mitochondria to LC3