Transfection of choanoflagellates illuminates their cell biology and the ancestry of animal septins.
-
PTSG_06009 (SrSeptin6) is a Group 1B (mammalian SEPT6-family) septin.
"with animal and fungal septins in Groups 1A (mammalian Septin 3 family), 1B (mammalian Septin 6 family), and 4 (S. cerevisiae Cdc12 family), respectively"
-
Tagged SrSeptin6 localises to the basal pole like SrSeptin2.
"found that SrSeptin6 displays the same basal localization as SrSeptin2 (Figure 4C)."
-
A role for septins in rosette development is a hypothesis, not a finding.
"a family of paralogous genes hypothesized to contribute to multicellular development in S. rosetta"
UniProt record for SrSeptin6 (F2UDE9)
-
SrSeptin6 has a septin-type G domain (residues 36-290) with G1, G3 and G4 motifs, and a coiled coil (317-366).
"PROSITE; PS51719; G_SEPTIN; 1."
Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features
Combined Automated Annotation using Multiple IEA Methods