Gene Ontology annotation through association of InterPro records with GO terms

Gene Ontology annotation based on Enzyme Commission mapping

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Catalysis of DNA cleavage and nucleoside triphosphate synthesis by NM23-H2/NDP kinase share an active site that implies a DNA repair function.

Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement.

Nuclear translocation of integrin cytoplasmic domain-associated protein 1 stimulates cellular proliferation.

A human protein-protein interaction network: a resource for annotating the proteome.

Characterization of the 3' --> 5' exonuclease activity found in human nucleoside diphosphate kinase 1 (NDK1) and several of its homologues.

Novel roles of NM23 proteins in skin homeostasis, repair and disease.

Histidine phosphorylation of the potassium channel KCa3.1 by nucleoside diphosphate kinase B is required for activation of KCa3.1 and CD4 T cells.

NM23-H1 tumor suppressor physically interacts with serine-threonine kinase receptor-associated protein, a transforming growth factor-beta (TGF-beta) receptor-interacting protein, and negatively regulates TGF-beta signaling.

NM23-H2 involves in negative regulation of Diva and Bcl2L10 in apoptosis signaling.

Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme.

Metastases suppressor NM23-H2 interaction with G-quadruplex DNA within c-MYC promoter nuclease hypersensitive element induces c-MYC expression.

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).

NM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III(1).

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.

Proteomic characterization of the human sperm nucleus.

Toward an understanding of the protein interaction network of the human liver.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

Membrane trafficking. Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodeling.

The maize (Zea mays L.) nucleoside diphosphate kinase1 (ZmNDPK1) gene encodes a human NM23-H2 homologue that binds and stabilizes G-quadruplex DNA.

Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function.

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS(G13D).

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis.

A novel serine/threonine-specific protein phosphotransferase activity of Nm23/nucleoside-diphosphate kinase.

Substrate specificity of human nucleoside-diphosphate kinase revealed by transient kinetic analysis.

(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3)

(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3)

Exocytosis of secretory granule lumen proteins

Exocytosis of ficolin-rich granule lumen proteins

NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP

NME1:2 hexamer phosphorylates 6TGDP to 6TGTP

NME1,2 hexamers phosphorylate RBV-DP

Falcon deep research report for human NME2