Annotation inferences using phylogenetic trees

A proteome-scale map of the human interactome network.

A reference map of the human binary protein interactome.

FAM111 protease activity undermines cellular fitness and is amplified by gain-of-function mutations in human disease.

Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

FAM111B dysregulation promotes malignancy in fibrosarcoma and POIKTMP and a low-cost method for its mutation screening.

Loss of FAM111B protease mutated in hereditary fibrosing poikiloderma negatively regulates telomere length.

Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components.

FAM111A protects replication forks from protein obstacles via its trypsin-like domain.