Gene Ontology annotation through association of InterPro records with GO terms
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
The FAR proteins of filarial nematodes: secretion, glycosylation and lipid binding characteristics.
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Recombinant Bm-FAR-1 from B. malayi binds all-trans-retinol, DAUDA, and oleic acid (by competition) in fluorescence-based assays, and produces a dramatic blue-shift in DAUDA fluorescence emission.
"Both were found to bind all-trans-retinol, (dansylamino) undecanoic acid (DAUDA), and oleic acid by competition."
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FAR proteins are released into the culture medium by all filarial species and developmental stages investigated, consistent with a secreted location.
"The proteins were released into culture medium by all the species and developmental stages investigated."