Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping

Gene Ontology annotation based on curation of immunofluorescence data

Gene Ontology annotation based on curation of intracellular localizations of expressed fusion proteins

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs.

Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping.

TDP43 is a human low molecular weight neurofilament (hNFL) mRNA-binding protein.

TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression.

Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity.

Peptidylprolyl isomerase A governs TARDBP function and assembly in heterogeneous nuclear ribonucleoprotein complexes.

USP7 and TDP-43: Pleiotropic Regulation of Cryptochrome Protein Stability Paces the Oscillation of the Mammalian Circadian Clock.

ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain.

The physical forces mediating self-association and phase-separation in the C-terminal domain of TDP-43.

TAR DNA-binding protein 43 (TDP-43) liquid-liquid phase separation is mediated by just a few aromatic residues.

A protein interaction framework for human mRNA degradation.

A human protein-protein interaction network: a resource for annotating the proteome.

Interaction of antiproliferative protein Tob with the CCR4-NOT deadenylase complex.

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS.

Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.

Elucidating novel hepatitis C virus-host interactions using combined mass spectrometry and functional genomics approaches.

Interaction of transactive response DNA binding protein 43 with nuclear factor κB in mild cognitive impairment with episodic memory deficits.

TDP-43 Inhibits NF-κB Activity by Blocking p65 Nuclear Translocation.

FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1.

A novel missense mutation of CMT2P alters transcription machinery.

Architecture of the human interactome defines protein communities and disease networks.

Chronic oxidative stress promotes GADD34-mediated phosphorylation of the TAR DNA-binding protein TDP-43, a modification linked to neurodegeneration.

TDP-43 Promotes Neurodegeneration by Impairing Chromatin Remodeling.

Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients.

Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.

OpenCell: Endogenous tagging for the cartography of human cellular organization.

Cryo-EM structure of the KLHL22 E3 ligase bound to an oligomeric metabolic enzyme.

An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity.

Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linking.

Molecular mechanism of oxidation-induced TDP-43 RRM1 aggregation and loss of function.

TDP-35 sequesters TDP-43 into cytoplasmic inclusions through binding with RNA.

ALS-Causing Mutations Significantly Perturb the Self-Assembly and Interaction with Nucleic Acid of the Intrinsically Disordered Prion-Like Domain of TDP-43.

Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2.

Cryo-EM structures of four polymorphic TDP-43 amyloid cores.

TDP-43 suppresses tau expression via promoting its mRNA instability.

Ubiquilin-2 (UBQLN2) binds with high affinity to the C-terminal region of TDP-43 and modulates TDP-43 levels in H4 cells: characterization of inhibition by nucleic acids and 4-aminoquinolines.

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

Deep research report on TARDBP