LAMP3 notes
Deep research (falcon / perplexity-lite) failed; notes from cached publications and UniProt Q9UQV4.
- DC-LAMP: lysosomal distribution in DC; in MIIC before MHC II reaches surface, then perinuclear lysosomes PMID:9768752.
- Lung-specific gene TSC403 homologous to LAMPs PMID:9721848.
- Influenza post-entry host factor PMID:21810281 -> symbiont entry IMP marked over-annotated.
- ATF4/UPR induced, promotes autophagic flux PMID:25681212.
- Cell surface pool in THP-1 relocates to Salmonella vacuoles PMID:27329040.
- IBA "establishment of protein localization to organelle" from LAMP2 CMA -> over-annotation.
Localization conclusion: lysosomal/late endosomal (MIIC) membrane, lamellar body membrane in type II pneumocytes; minor
cell-surface pool (luminal domain exposed when at surface). Mostly intracellular.