Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Combined Automated Annotation using Multiple IEA Methods
Heat shock protein 90 as an endogenous protein enhancer of inducible nitric-oxide synthase.
Identification of the nuclear receptor CAR:HSP90 complex in mouse liver and recruitment of protein phosphatase 2A in response to phenobarbital.
Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease.
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.
The mammalian CHORD-containing protein melusin is a stress response protein interacting with Hsp90 and Sgt1.
The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C.
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.
Hectd1 regulates intracellular localization and secretion of Hsp90 to control cellular behavior of the cranial mesenchyme.
RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.
Dynamic nucleotide-dependent interactions of cysteine- and histidine-rich domain (CHORD)-containing Hsp90 cochaperones Chp-1 and melusin with cochaperones PP5 and Sgt1.
Hsp90 activity is necessary to acquire a proper neuronal polarization.
Interaction of a Novel Chaperone PhLP2A With the Heat Shock Protein Hsp90.
REV-ERBα influences the stability and nuclear localization of the glucocorticoid receptor.
Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.
ZMYND10 functions in a chaperone relay during axonemal dynein assembly.
Ubiquitin binds Vcp:Hdac6:Hsp90:Hsf1
PolyUb-Misfolded Proteins:Hdac6 dissociate from complex
Hsp90aa1 Falcon deep research report
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Hsp90aa1 encodes cytosolic HSP90-alpha, a dimeric ATP-dependent molecular chaperone.
"**Hsp90aa1 encodes HSP90α**, a highly abundant **ATP-dependent molecular chaperone** that functions as a dimer"
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ATP binding and hydrolysis drive the HSP90-alpha chaperone cycle for client loading and maturation.
"ATP binding and hydrolysis drive a conformational cycle through open/closed and nucleotide-bound states that orchestrate client loading, activation/maturation, and release."
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HSP90-alpha is primarily cytosolic, with non-core extracellular and male-germline contexts.
"Hsp90α is a **cytosolic** Hsp90 isoform"