Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Identification and characterization of photomedins: novel olfactomedin-domain-containing proteins with chondroitin sulphate-E-binding activity.
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Mouse photomedin-1 (Olfml2a) is secreted as a disulfide-bonded, O-glycosylated dimer and is proteolytically processed after secretion.
"photomedin-1 was
proteolytically processed in the middle of the molecule after secretion"
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Photomedins preferentially bind chondroitin sulfate E and heparin among tested ECM components.
"photomedins
preferentially bound to chondroitin sulphate-E and heparin"
Transcriptome-based systematic identification of extracellular matrix proteins.
Neuronal proteins are novel components of podocyte major processes and their expression in glomerular crescents supports their role in crescent formation.
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Olfml2a is expressed exclusively by podocytes in the glomerulus and localizes to podocyte major processes; it is co-expressed with podocyte markers in human glomerular crescents.
"These proteins were expressed exclusively by podocytes, wherein they localized to major processes"
human/OLFML2A/OLFML2A-uniprot.txt