Gene Ontology annotation through association of InterPro records with GO terms

Use of the ND evidence code for Gene Ontology (GO) terms

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

PMID:16303567

A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

The abstract reports deletion of 175 meiotically up-regulated S. pombe genes and identification of seven named genes required for critical meiotic events; it does not mention mug151, so the gene-specific result cannot be verified from the cached abstract.

"we have deleted 175 meiotically upregulated genes and found seven genes not previously reported to be critical for meiotic events."

PMID:11859360

The genome sequence of Schizosaccharomyces pombe.

PMID:38065098

SAP30BP interacts with RBM17/SPF45 to promote splicing in a subset of human short introns.

Human SAP30BP (a factor previously implicated in transcriptional control) is an essential splicing cofactor for RBM17/SPF45; this documents a splicing role for the SAP30BP/HCNGP family that mug151 belongs to, in human rather than S. pombe.

file:SCHPO/mug151/mug151-deep-research-falcon.md

Falcon (Edison Scientific) deep research report: S. pombe mug151 (Q10069 / SPAC3H1.03) functional annotation.

The literature search found no mug151-focused primary characterization and concluded that its molecular activity, partners, pathway, phenotype, and experimental localization remain unknown; SAP30BP/HCNGP family membership supports only a tentative regulatory-adaptor hypothesis.

"Mug151 (SPAC3H1.03; UniProt Q10069) is an uncharacterized protein of *Schizosaccharomyces pombe* whose gene was identified as meiotically up-regulated. The protein carries predicted SAP30BP/HCNGP-related sequence signatures, but its molecular activity, binding partners, pathway, phenotype, and subcellular localization have not been experimentally established."

file:SCHPO/mug151/mug151-uniprot.txt

UniProtKB Q10069 (MU151_SCHPO), Schizosaccharomyces pombe mug151

UniProt assigns mug151 a role in meiosis from PMID:16303567 with experimental evidence and assigns nuclear localization by similarity.

"FUNCTION: Has a role in meiosis. {ECO:0000269|PubMed:16303567}."
UniProt predicts nuclear localization by similarity.

"SUBCELLULAR LOCATION: Nucleus {ECO:0000250}."