NCU04937: ProtNLM2 location review

Source method: ProtNLM2. Source version: live API snapshot 2026-09-09T03:00:51.831347+00:00. Accession: Q7S3T0. Raw source: NCU04937-protnlm-source.json.

Exact location claims

• Original identifier: SL-0191. Original text: Nucleus.

Assessment: UNC (1). No target localization experiment, reliable nuclear-targeting feature or supported nuclear family placement was identified. The current sequence is only 114 residues and largely glutamine-rich. Its donor Q96EK4 is human THAP11, a 314-residue transcription factor; the recorded phmmer score 29.1 supplies no alignment showing conservation of its functional DNA-binding region. Neither a predicted coiled coil nor small size establishes nuclear enrichment. The nuclear claim is plausible but not validated or refuted. Donor record: NCU04937-donor-Q96EK4.json.

Inspected evidence

• file:NEUCR/NCU04937/NCU04937-uniprot.txt: “FT COILED 52..104”

Complete location evidence objects

{
  "commentType": "SUBCELLULAR LOCATION",
  "subcellularLocations": [
    {
      "location": {
        "evidences": [
          {
            "evidenceCode": "ECO:0008006",
            "id": "ProtNLM2",
            "properties": [
              {
                "key": "model_score",
                "value": "0.91"
              },
              {
                "key": "phmmer_accession",
                "value": "Q96EK4"
              },
              {
                "key": "phmmer_score",
                "value": "29.1"
              }
            ],
            "source": "Google"
          }
        ],
        "id": "SL-0191",
        "value": "Nucleus"
      }
    }
  ]
}