Annotation inferences using phylogenetic trees

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

UniProtKB entry P22304 (IDS_HUMAN)

Expression of five iduronate-2-sulfatase site-directed mutations.

The effect of four mutations on the expression of iduronate-2-sulfatase in mucopolysaccharidosis type II.

Sulphatase activities are regulated by the interaction of sulphatase-modifying factor 1 with SUMF2.

Hunter syndrome: isolation of an iduronate-2-sulfatase cDNA clone and analysis of patient DNA.

Insights into Hunter syndrome from the structure of iduronate-2-sulfatase.

IDS hydrolyses Heparan sulfate chain(5)

IDS hydrolyses dermatan sulfate (Chebi:63517 chain)

Defective IDS does not hydrolyse dermatan sulfate (Chebi:63517 chain)

Defective IDS does not hydrolyse Heparan sulfate chain(5)