Eaf6 (Q9VRN3) review notes

MEAF6/EAF6 homolog; Enok complex subunit required for H3K23ac. PMID:27198229
Also in Tip60/NuA4-type DOM-A complex. PMID:32432549
Decisions: shared Enok complex conventions; NuA4 complex IBA/IDA rows ACCEPT (EAF6 is a shared subunit of MYST complexes), but the DOM-A IPI row (PMID:32432549) set to UNDECIDED after deep research; generic HAT complex IEA MODIFY -> both specific complexes.

Deep research (falcon, added after initial review)

Eaf6-deep-research-falcon.md: strongest fly evidence places Eaf6 in the Enok-Br140-Ing5 complex ["Affinity purification and mass spectrometry of functional, tagged Br140 recovered Eaf6 together with Enok and Ing5."]; Eaf6 mutant hemocytes show mildly reduced H3K23ac (2020 preprint). It reports Eaf6 was absent from the stringent 2020 DOM-A purification (PMID:32432549), while a 2025 preprint links Eaf6 abundance to Tip60. The cached PMID:32432549 text does not mention Eaf6, so the DOM-A IPI row was changed from ACCEPT to UNDECIDED and the NuA4 core function was dropped (raised as a suggested question).

Core function now carries GO:0010698 as molecular_function alongside contributes_to GO:0043994.
One NuA4 position: rows are judged by their own cited evidence. IBA (GO_REF:0000033) ACCEPT as phylogenetic inference (EAF6/MEAF6 is a NuA4/TIP60 subunit in yeast, Candida, human). Both experimental rows UNDECIDED: PMID:15528408 is abstract-only and does not mention Eaf6; PMID:32432549 cached text does not mention Eaf6 and deep research reports Eaf6 absent from its stringent DOM-A purification. GO:0035267 removed as a MODIFY replacement for GO:0000123 (now GO:0070776 only). Description and suggested question state fly NuA4 membership is unresolved.
reference_review added: PMID:32432549 relevance LOW, correctness UNVERIFIED.