Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Combined Automated Annotation using Multiple IEA Methods

Characterization of an amyloid precursor protein-binding protein Fe65L2 and its novel isoforms lacking phosphotyrosine-interaction domains.

The amyloid precursor protein and its regulatory protein, FE65, in growth cones and synapses in vitro and in vivo.

Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism.

A pilot proteomic study of amyloid precursor interactors in Alzheimer's disease.

A quantitative protein interaction network for the ErbB receptors using protein microarrays.

The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport.

Structural basis for polyproline recognition by the FE65 WW domain.

Regulation of FE65 nuclear translocation and function by amyloid beta-protein precursor in osmotically stressed cells.

Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions.

FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4.

The APP intracellular domain (AICD) potentiates ER stress-induced apoptosis.

Phosphorylation of LRP1 regulates the interaction with Fe65.

FE65 interacts with ADP-ribosylation factor 6 to promote neurite outgrowth.

Amyloid beta a4 precursor protein-binding family B member 1 (FE65) interactomics revealed synaptic vesicle glycoprotein 2A (SV2A) and sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) as new binding proteins in the human brain.

Regulation of neuronal survival and morphology by the E3 ubiquitin ligase RNF157.

Screening of APP interaction proteins by DUALmembrane yeast two-hybrid system.

Quantitative interaction proteomics reveals differences in the interactomes of amyloid precursor protein isoforms.

HENA, heterogeneous network-based data set for Alzheimer's disease.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

Insulin stimulates atypical protein kinase C-mediated phosphorylation of the neuronal adaptor FE65 to potentiate neurite outgrowth by activating ARF6-Rac1 signaling.

The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein.

cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein.

Fe65L2: a new member of the Fe65 protein family interacting with the intracellular domain of the Alzheimer's beta-amyloid precursor protein.

APBB1 and MAPK8 bind diphosphorylated H2AFX

Deep research report on APBB1