Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt.

Gene Ontology annotation based on curation of immunofluorescence data

Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity

Electronic Gene Ontology annotations created by ARBA machine learning models

Calyculin A inhibits expression of CD8alpha but not CD4 in human peripheral blood T cells.

Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G.

Influence of human CD8 on antigen recognition by T-cell receptor-transduced cells.

FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection.

Computational design and crystal structure of an enhanced affinity mutant human CD8 alphaalpha coreceptor.

CD8 Raft localization is induced by its assembly into CD8alpha beta heterodimers, Not CD8alpha alpha homodimers.

CD8αα and -αβ isotypes are equally recruited to the immunological synapse through their ability to bind to MHC class I.

The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex.

Molecular biology and function of CD4 and CD8.

Alternatively spliced mRNA encodes a secreted form of human CD8 alpha. Characterization of the human CD8 alpha gene.

Polymorphism in the alpha 3 domain of HLA-A molecules affects binding to CD8.

Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2.

Zinc is essential for binding of p56(lck) to CD4 and CD8alpha.

TCR complex interacts with peptide antigen-presenting MHC Class I

Deep research on CD8A function