Fetched with just fetch-gene PSEAE Q9HUA1 --alias PA5082 (no gene symbol in
UniProt; locus tag used as folder name). Accession Q9HUA1 matches the worklist
(rank 325). Unreviewed TrEMBL entry, 299 aa, SignalP signal peptide 1-22.
Reviewed with PA1342 (AatJ, Q9I402), the other PseudoCAP seed of the same
node, and checked against genes/PSEAE/PA5085 (DguR, the activator of the
dguABC operon; same paper). No deep-research provider was used.
Assessment: a dguC mutant with a slight growth defect on D-Glu is a weak,
indirect readout, but the abstract positively reports it for this gene, and a
periplasmic binding protein in a D-Glu-induced catabolic operon has no
plausible role in D-Glu utilisation other than substrate capture for transport.
The row is accepted as the gene's (weakly supported) core process. The AatJMQP
system is the main D-Glu route, so DguC is at most a secondary binding protein.
PTN004739212 (GO:0006865 amino acid transport; seeds Q9HUA1, Q9I402, E. coli
GltI P37902). The full clade analysis is in genes/PSEAE/PA1342/PA1342-notes.md
(recorded once there): an SBP_bac_3 amino acid binding protein clade grounded
by E. coli GltI (IDA L-glutamate transmembrane transport), so the IBD does not
depend on this seed.
| PTN node | node term | n_seeds | leaf IBAs | seed annotation (term, evidence, PMID) | verdict | rationale | other seeds | IBD stands without this seed? |
|---|---|---|---|---|---|---|---|---|
| PTN004739212 | GO:0006865 amino acid transport | 3 | 31 (14 taxa) | GO:0042940 D-amino acid transport, IMP, PMID:25082951 (PseudoCAP) | SOUND | The abstract reports a dguC lesion that slightly impairs growth on D-Glu; weak, but for a periplasmic binding protein in the D-Glu-induced dgu operon it supports D-amino acid transport, and it amply supports the general node term. | PA1342 Q9I402 (same paper); E. coli GltI P37902 (IDA) | Yes, on E. coli GltI alone (see PA1342 notes). No GO_CENTRAL defect. |
Defects filed: none.