GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
PMID:11163187
Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon.
PMID:11546873
Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex.
PMID:11546874
Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1.
PMID:12417715
Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay.
PMID:14636577
Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7.
PMID:16601204
Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation.
PMID:17916692
Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends.
PMID:19503078
A UPF3-mediated regulatory switch that maintains RNA surveillance.
PMID:20479275
Insights into the recruitment of the NMD machinery from the crystal structure of a core EJC-UPF3b complex.
PMID:25220460
The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex.
PMID:27040500
The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay.
PMID:31131562
Nonsense-mediated mRNA decay: The challenge of telling right from wrong in a complex transcriptome.
PMID:35640974
Structures of nonsense-mediated mRNA decay factors UPF3B and UPF3A in complex with UPF2 reveal molecular basis for competitive binding and for neurodevelopmental disorder-causing mutation.
Reactome:R-HSA-927813
Reactome NMD pathway (cytosol localization of UPF3A)
Reactome:R-HSA-927832
Reactome NMD pathway (cytosol localization of UPF3A)
Reactome:R-HSA-927836
Reactome NMD pathway (cytosol localization of UPF3A)
Reactome:R-HSA-927889
Reactome NMD pathway (cytosol localization of UPF3A)