Gene Ontology annotation through association of InterPro records with GO terms

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

MAP kinase dynamics in response to pheromones in budding yeast.

Fus1p interacts with components of the Hog1p mitogen-activated protein kinase and Cdc42p morphogenesis signaling pathways to control cell fusion during yeast mating.

Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes.

The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway.

Function of the MAPK scaffold protein, Ste5, requires a cryptic PH domain.

A mechanism for cell-cycle regulation of MAP kinase signaling in a yeast differentiation pathway.

Spatial regulation of Fus3 MAP kinase activity through a reaction-diffusion mechanism in yeast pheromone signalling.

Recognition of non-canonical peptides by the yeast Fus1p SH3 domain: elucidation of a common mechanism for diverse SH3 domain specificities.

The Ste5 scaffold directs mating signaling by catalytically unlocking the Fus3 MAP kinase for activation.

Exploitation of latent allostery enables the evolution of new modes of MAP kinase regulation.

Association of the yeast pheromone response G protein beta gamma subunits with the MAP kinase scaffold Ste5p.

Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade.

Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae.

Ste5 RING-H2 domain: role in Ste4-promoted oligomerization for yeast pheromone signaling.

Interaction of a G-protein beta-subunit with a conserved sequence in Ste20/PAK family protein kinases.

Membrane recruitment of the kinase cascade scaffold protein Ste5 by the Gbetagamma complex underlies activation of the yeast pheromone response pathway.

UniProtKB entry P32917 (STE5_YEAST)

Falcon deep research report for STE5