GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000116
Automatic Gene Ontology annotation based on Rhea mapping
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
PMID:15775970
Export of mitochondrial AIF in response to proapoptotic stimuli depends on processing at the intermembrane space.
PMID:16365034
AIFsh, a novel apoptosis-inducing factor (AIF) pro-apoptotic isoform with potential pathological relevance in human cancer.
PMID:16644725
Identification and characterization of AIFsh2, a mitochondrial apoptosis-inducing factor (AIF) isoform with NADH oxidase activity.
PMID:16713569
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
PMID:17094969
Apoptosis-inducing factor (AIF) inhibits protein synthesis by interacting with the eukaryotic translation initiation factor 3 subunit p44 (eIF3g).
PMID:18309324
No death without life: vital functions of apoptotic effectors.
PMID:20111043
A brain-specific isoform of mitochondrial apoptosis-inducing factor: AIF2.
PMID:20833797
Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes.
PMID:21364629
Vital function of PRELI and essential requirement of its LEA motif.
PMID:21715506
Comprehensive proteomic analysis of influenza virus polymerase complex reveals a novel association with mitochondrial proteins and RNA polymerase accessory factors.
PMID:22371500
Steroid receptor coactivator-interacting protein (SIP) inhibits caspase-independent apoptosis by preventing apoptosis-inducing factor (AIF) from being released from mitochondria.
PMID:23217327
Cowchock syndrome is associated with a mutation in apoptosis-inducing factor.
PMID:24914854
Structural insights into the coenzyme mediated monomer-dimer transition of the pro-apoptotic apoptosis inducing factor.
PMID:26004228
Interaction between AIF and CHCHD4 Regulates Respiratory Chain Biogenesis.
PMID:27178839
Structure/Function Relations in AIFM1 Variants Associated with Neurodegenerative Disorders.
PMID:33168626
The 89-kDa PARP1 cleavage fragment serves as a cytoplasmic PAR carrier to induce AIF-mediated apoptosis.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
PMID:34800366
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
PMID:35994922
AIFM1 beyond cell death: An overview of this OXPHOS-inducing factor in mitochondrial diseases.
PMID:39806100
NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism.
PMID:9989411
Molecular characterization of mitochondrial apoptosis-inducing factor.
PMID:21467298
Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos).
PMID:18056262
Scythe regulates apoptosis-inducing factor stability during endoplasmic reticulum stress-induced apoptosis.
PMID:39979311
AIF3 splicing variant elicits mitochondrial malfunction via the concurrent dysregulation of electron transport chain and glutathione-redox homeostasis.
PMID:19418225
Apoptosis-inducing factor plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells.
UniProt:O95831
UniProtKB O95831 (AIFM1_HUMAN): apoptosis-inducing factor 1, mitochondrial