GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:11379879
Segregation of a mutation in CNGB1 encoding the beta-subunit of the rod cGMP-gated channel in a family with autosomal recessive retinitis pigmentosa.
PMID:20890309
Growth factor receptor-bound protein 14: a new modulator of photoreceptor-specific cyclic-nucleotide-gated channel.
PMID:34699778
Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
PMID:7479749
Mutations in the gene encoding the alpha subunit of the rod cGMP-gated channel in autosomal recessive retinitis pigmentosa.
Reactome:R-HSA-2514865
cGMP dissociates from CNG channels
Reactome:R-HSA-2514867
cGMP:CNG transports Na+ and Ca2+ into the rod outer segment
Reactome:R-HSA-3229181
CALM1:Ca2+ binds CNG channel
Reactome:R-HSA-74031
cGMP binds CNG channel to form cGMP:CNG channel
PMID:33651975
Structural mechanisms of gating and selectivity of human rod CNGA1 channel.
PMID:1379636
Human rod photoreceptor cGMP-gated channel: amino acid sequence, gene structure, and functional expression.
PMID:10352032
Divalent cation selectivity is a function of gating in native and recombinant cyclic nucleotide-gated ion channels from retinal photoreceptors.
PMID:15634774
Impaired channel targeting and retinal degeneration in mice lacking the cyclic nucleotide-gated channel subunit CNGB1.
file:human/CNGA1/CNGA1-source-evidence.json
CNGA1 source and assay provenance